Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | BPTF | Q12830 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 4/20 | 0.38 |
| ▸ | CCR2 | P41597 | 4/20 | 0.38 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.38 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15496950 | 0.89 | GPR119 (0.48) | LMNAALDH1A1AKR1C3ADRB1MEN1 | |
| SCHEMBL24824178 | 0.83 | ADRB1 (0.47) | AKR1C3ADRB1MEN1KMT2AGPR119 | |
| SCHEMBL81924 | 0.79 | HRH4 (0.46) | ADRB1 | |
| SCHEMBL22466087 | 0.79 | MAPT (0.50) | LMNAALDH1A1MEN1KMT2ABPTF | |
| SCHEMBL17661012 | 0.79 | L3MBTL1 (0.41) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL28956356 | 0.78 | BPTF (0.66) | ADRB1MEN1KMT2ABPTF | |
| SCHEMBL20510583 | 0.78 | BPTF (0.66) | ADRB1MEN1KMT2ABPTF | |
| SCHEMBL17665171 | 0.78 | AKR1C3 (0.45) | LMNAALDH1A1AKR1C3ADRB1MEN1 | |
| SCHEMBL20217192 | 0.76 | AKR1C3 (0.44) | ALDH1A1AKR1C3ADRB1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL30307836 | 0.76 | BPTF (0.63) | ADRB1MEN1KMT2ABPTF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212158-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | BRISTOL MYERS SQUIBB CO (US) | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212158-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | LGALS3, LGALS1, LGALS3BP | LMNA 1394/4885ALDH1A1 2713/4885AKR1C3 3789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.