SCHEMBL25857066

SCHEMBL25857066

C=CC1OC(C=C)C2C(=O)N(CCNC(=S)NC(=N)Nc3ccccc3)C(=O)C12

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.43
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 3/20 0.35
GAA P10253 2/20 0.35
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
TP53 P04637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25857076 0.93 ALDH1A1 (0.38) ALDH1A1KMT2AMEN1LMNAMAPT
SCHEMBL24746661 0.85 ALDH1A1 (0.47) ALDH1A1MAPTGAANPC1RAB9A
SCHEMBL24746985 0.83 ALDH1A1 (0.39) ALDH1A1KMT2AMAPTGAANPC1
SCHEMBL25857073 0.79 ALDH1A1 (0.42) ALDH1A1KMT2AMEN1LMNAMAPT
SCHEMBL25857060 0.76 ALDH1A1 (0.45) ALDH1A1KMT2AMEN1NPC1RAB9A
SCHEMBL25857062 0.76 ALDH1A1 (0.45) ALDH1A1KMT2AMEN1MAPTNPC1
SCHEMBL25857160 0.73 ALDH1A1 (0.31) ALDH1A1NPC1RAB9ASMN1; SMN2TP53
SCHEMBL25857181 0.72 ALDH1A1 (0.38) ALDH1A1KMT2AMEN1LMNAMAPT
SCHEMBL24746659 0.71 ALDH1A1 (0.48) ALDH1A1KMT2AMEN1LMNAGAA
SCHEMBL25857050 0.71 ALDH1A1 (0.43) ALDH1A1KMT2AMEN1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11801228-B2 Modified guanidine-containing polymers for biologic delivery THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2023-10-31 US disclosed
US-20230225982-A1 MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230225982-A1 MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY GMPS, RNMT, GUCY1A1 ALDH1A1 1829/4885KMT2A 2590/4885MEN1 2661/4885
US-11801228-B2 Modified guanidine-containing polymers for biologic delivery GMPS, RNMT, GUCY1A1 ALDH1A1 1829/4885KMT2A 2590/4885MEN1 2661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.