SCHEMBL25867338

SCHEMBL25867338

CCOC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c(C)cc(O)cc1C)NC(=O)[C@@H](CCCNC(=N)NC(=O)OCC)NC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 7/20 0.49
REN P00797 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24146439 0.94 SIRT2 (0.46)
SCHEMBL25867315 0.94 CCKBR (0.50) CCKBRREN
SCHEMBL25865433 0.91 NPY4R (0.52)
SCHEMBL24146441 0.90 OPRM1 (0.49)
SCHEMBL19862397 0.90 NPY4R (0.52) CCKBRREN
SCHEMBL18048887 0.90 NPY4R (0.52) CCKBRREN
SCHEMBL19862098 0.90 NPY4R (0.52) CCKBRREN
SCHEMBL19862399 0.90 NPY4R (0.52) CCKBRREN
SCHEMBL21627105 0.89 CCKBR (0.53) CCKBRREN
SCHEMBL16862457 0.89 CCKBR (0.53) CCKBRREN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230227499-A1 PRODRUGS OF MITOCHONDRIA-TARGETING OLIGOPEPTIDES STEALTH BIOTHERAPEUTICS INC. 2023-07-20 US disclosed
US-20230227499-A1 PRODRUGS OF MITOCHONDRIA-TARGETING OLIGOPEPTIDES STEALTH BIOTHERAPEUTICS INC. 2023-07-20 US disclosed
EP-4168424-A1 PRODRUGS OF MITOCHODRIA-TARGETING OLIGOPEPTIDES Stealth BioTherapeutics Inc. (US) 2023-04-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230227499-A1 PRODRUGS OF MITOCHONDRIA-TARGETING OLIGOPEPTIDES PITRM1, NME4, PDF CCKBR 1024/4885REN 4371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.