Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 8/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 11/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2581672 | 0.87 | DRD4 (0.53) | SIGMAR1 | |
| SCHEMBL2583662 | 0.84 | BCHE (0.47) | — | |
| SCHEMBL2585658 | 0.81 | CCR2 (0.46) | CCR3MCHR1 | |
| SCHEMBL2585643 | 0.78 | MEN1 (0.43) | — | |
| SCHEMBL2564778 | 0.73 | MCHR1 (0.87) | CCR3MCHR1SIGMAR1 | |
| SCHEMBL2585594 | 0.73 | ALDH1A1 (0.49) | — | |
| SCHEMBL2582036 | 0.72 | GAA (0.52) | — | |
| SCHEMBL4264547 | 0.72 | KMT2A (0.48) | — | |
| SCHEMBL2585373 | 0.70 | ALDH1A1 (0.54) | — | |
| SCHEMBL2586727 | 0.70 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048879-B2 | Substituted 4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyridine compounds and use thereof for producing medicaments | GRUENENTHAL GMBH (DE) | 2011-11-01 | — | — | US | claimed |
| US-8048879-B2 | Substituted 4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyridine compounds and use thereof for producing medicaments | GRUENENTHAL GMBH (DE) | 2011-11-01 | — | — | US | disclosed |