SCHEMBL25875494

SCHEMBL25875494

Cc1cc(Br)ccc1OC(F)(F)C(C)(F)F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.39
AAK1 Q2M2I8 2/20 0.36
ALDH1A1 P00352 4/20 0.35
HPGD P15428 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
POLB P06746 1/20 0.35
TDP1 Q9NUW8 2/20 0.35
MAPK1 P28482 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
LMNA P02545 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPC1 O15118 1/20 0.35
TP53 P04637 1/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
CASP3 P42574 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
SENP6 Q9GZR1 1/20 0.35
SSTR4 P31391 1/20 0.34
KMT2A Q03164 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29943103 0.83 SCN5A (0.41) RAB9AALDH1A1HPGDNPSR1POLB
SCHEMBL640891 0.83 SCN5A (0.41) RAB9AALDH1A1HPGDNPSR1POLB
SCHEMBL25875497 0.81 ACHE (0.38) RAB9AALDH1A1HPGDTDP1MAPK1
SCHEMBL13019865 0.81 RAB9A (0.42) RAB9AAAK1ALDH1A1HPGDNPSR1
SCHEMBL25875505 0.81 L3MBTL1 (0.34) RAB9AALDH1A1NPSR1POLBTDP1
SCHEMBL25875508 0.81 TSHR (0.39) RAB9AAAK1ALDH1A1HPGDNPSR1
SCHEMBL2033955 0.77 RAB9A (0.38) RAB9AAAK1ALDH1A1HPGDNPSR1
SCHEMBL24901452 0.76 ALDH1A1 (0.43) RAB9AAAK1ALDH1A1HPGDNPSR1
SCHEMBL13064438 0.75 RAB9A (0.42) RAB9AAAK1ALDH1A1HPGDNPSR1
SCHEMBL18532071 0.74 RAB9A (0.38) RAB9AAAK1ALDH1A1HPGDNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814463-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-11-14 US disclosed
US-20230227604-A1 FLUORINATED AROMATIC POLYMER AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2023-07-20 US disclosed
US-11643500-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-05-09 US disclosed