SCHEMBL25875505

SCHEMBL25875505

CC(F)(F)C(F)(F)Oc1ccc(Br)cc1N

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.34
ALDH1A1 P00352 4/20 0.34
MAPK1 P28482 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
GAA P10253 2/20 0.33
KDM4E B2RXH2 2/20 0.33
RAB9A P51151 1/20 0.33
GLA P06280 1/20 0.33
SLC6A4 P31645 1/20 0.33
PTGDR2 Q9Y5Y4 2/20 0.33
POLB P06746 1/20 0.32
HRH4 Q9H3N8 1/20 0.32
MGAM O43451 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
CYP3A4 P08684 1/20 0.32
NPY1R P25929 1/20 0.31
NPY2R P49146 1/20 0.31
MAPT P10636 5/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30279579 0.86 L3MBTL1 (0.36) L3MBTL1ALDH1A1MAPK1TDP1GAA
SCHEMBL526369 0.82 HRH4 (0.40) L3MBTL1ALDH1A1MAPK1TDP1KDM4E
SCHEMBL25875494 0.81 RAB9A (0.39) L3MBTL1ALDH1A1MAPK1TDP1KDM4E
SCHEMBL25875506 0.81 ALDH1A1 (0.53) L3MBTL1ALDH1A1TDP1GAARAB9A
SCHEMBL25875508 0.79 TSHR (0.39) ALDH1A1MAPK1TDP1KDM4ERAB9A
SCHEMBL30279586 0.77 TRPV1 (0.39) L3MBTL1ALDH1A1MAPK1TDP1KDM4E
SCHEMBL30279587 0.77 TRPV1 (0.39) L3MBTL1ALDH1A1MAPK1TDP1KDM4E
SCHEMBL29689196 0.71 ALDH1A1 (0.59) L3MBTL1ALDH1A1TDP1GAAPOLB
SCHEMBL111151 0.71 ALDH1A1 (0.59) L3MBTL1ALDH1A1TDP1GAAPOLB
SCHEMBL21630357 0.70 APLNR (0.38) L3MBTL1ALDH1A1MAPK1TDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814463-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-11-14 US disclosed
US-20230227604-A1 FLUORINATED AROMATIC POLYMER AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2023-07-20 US disclosed
US-11643500-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-05-09 US disclosed