Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RNASEH1 | O60930 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15956900 | 0.84 | SMN1; SMN2 (0.52) | ALDH1A1MAPTPDE3BPDE3ASMN1; SMN2 | |
| SCHEMBL24129894 | 0.77 | L3MBTL1 (0.40) | ALDH1A1MAPTPDE3BPDE3ASMN1; SMN2 | |
| SCHEMBL25309056 | 0.77 | L3MBTL1 (0.40) | ALDH1A1MAPTPDE3BPDE3ASMN1; SMN2 | |
| SCHEMBL18419869 | 0.77 | KMT2A (0.43) | ALDH1A1MAPTSMN1; SMN2KMT2AKDM4E | |
| SCHEMBL19037422 | 0.76 | LMNA (0.49) | ALDH1A1SMN1; SMN2KMT2ARNASEH1LMNA | |
| SCHEMBL15956955 | 0.76 | RNASEH1 (0.50) | KMT2ARNASEH1LMNA | |
| SCHEMBL21065619 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL15964606 | 0.75 | MMP2 (0.49) | ALDH1A1MAPTPDE3BPDE3ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL15956818 | 0.75 | RNASEH1 (0.49) | MAPTKMT2AKDM4ERNASEH1 | |
| Diphenylmethane SCHEMBL26922258 | 0.75 | ALDH1A1 (0.56) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227435-A1 | SMALL MOLECULE MODULATORS OF IL-17 | LEO PHARMA A/S (DK) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227435-A1 | SMALL MOLECULE MODULATORS OF IL-17 | IL17A, IL2, IL23R | ALDH1A1 448/4885MAPT 559/4885PDE3B 266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.