Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.66 |
| ▸ | DRD2 | P14416 | 4/20 | 0.66 |
| ▸ | HTR6 | P50406 | 4/20 | 0.66 |
| ▸ | HTR2A | P28223 | 3/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.66 |
| ▸ | HRH1 | P35367 | 2/20 | 0.66 |
| ▸ | HTR7 | P34969 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 10/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.63 |
| ▸ | MEN1 | O00255 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | MPI | P34949 | 1/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.54 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22473980 | 0.81 | ALDH1A1 (0.65) | HTR1ADRD2HTR6HTR2ASLC6A4 | |
| SCHEMBL13243203 | 0.81 | MAPT (0.61) | HTR1ADRD2HTR6HTR2ASLC6A4 | |
| SCHEMBL19543287 | 0.79 | ALDH1A1 (0.54) | HTR1ADRD2HTR6HTR2ASLC6A4 | |
| SCHEMBL29969387 | 0.79 | CYP1B1 (0.67) | KMT2AMEN1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL92102 | 0.79 | CYP1B1 (0.67) | KMT2AMEN1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL2469135 | 0.77 | CYP1B1 (0.64) | KMT2AMEN1ALDH1A1SMN1; SMN2HPGD | |
| Water SCHEMBL3507216 | 0.77 | CYP1B1 (0.64) | KMT2AMEN1ALDH1A1SMN1; SMN2HPGD | |
| Bromide SCHEMBL17510003 | 0.77 | CYP1B1 (0.64) | KMT2AMEN1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL14288790 | 0.77 | DRD2 (0.58) | HTR1ADRD2HTR6HTR2ASLC6A4 | |
| SCHEMBL26224662 | 0.77 | HTR1A (0.54) | HTR1ADRD2HTR6HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230338562-A1 | METHODS FOR THE PREPARATION OF LINKER PAYLOAD CONSTRUCTS | SYNAFFIX B.V. (NL) | 2023-10-26 | — | — | US | disclosed |
| US-20230235082-A1 | SITE-SPECIFIC ANTIBODY CONJUGATES AND THE METHODS FOR PREPARATION OF THE SAME | GLYCO-THERAPY BIOTECHNOLOGY CO., LTD. (CN) | 2023-07-27 | — | — | US | disclosed |
| US-20230226208-A1 | METHODS FOR THE PREPARATION OF BIOCONJUGATES | SYNAFFIX B.V. (NL) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230338562-A1 | METHODS FOR THE PREPARATION OF LINKER PAYLOAD CONSTRUCTS | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, DRD3, SNRPD3 | HTR1A 982/4885DRD2 14/4885HTR6 908/4885 |
| US-20230235082-A1 | SITE-SPECIFIC ANTIBODY CONJUGATES AND THE METHODS FOR PREPARATION OF THE SAME | FUT5, FUT6, SIGLEC7 | HTR1A 4404/4885DRD2 3943/4885HTR6 3637/4885 |
| US-20230226208-A1 | METHODS FOR THE PREPARATION OF BIOCONJUGATES | ZYX, ALG1, MLX | HTR1A 3800/4885DRD2 187/4885HTR6 4299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.