Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18171927 | 0.83 | TDP1 (0.58) | TP53TDP1TRPA1CNR1CNR2 | |
| SCHEMBL16852427 | 0.81 | TRPA1 (0.48) | TP53TDP1TRPA1ALOX15HSD17B10 | |
| SCHEMBL573212 | 0.80 | AR (0.47) | TP53TDP1TRPA1ALOX15HSD17B10 | |
| SCHEMBL25878367 | 0.79 | TRPA1 (0.50) | TP53TDP1TRPA1CNR1CNR2 | |
| SCHEMBL26968681 | 0.78 | LMNA (0.54) | TP53TDP1CNR1CNR2ALDH1A1 | |
| SCHEMBL197716 | 0.78 | ALDH1A1 (0.52) | TP53TDP1TRPA1ALOX15HSD17B10 | |
| SCHEMBL1513628 | 0.75 | ATM (0.48) | TP53TRPA1ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL16122277 | 0.75 | ALDH1A1 (0.56) | TP53TDP1TRPA1CNR1CNR2 | |
| SCHEMBL5684790 | 0.74 | CASP1 (0.61) | TP53TDP1TRPA1CNR1CNR2 | |
| SCHEMBL21125927 | 0.74 | ACHE (0.48) | TP53TDP1TRPA1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659801-B1 | Polyimide | MITSUI CHEMICALS INC (JP) | 1999-03-10 | — | — | EP | disclosed |
| US-5484880-A | HEAT RESISTANT POLYMERS FOR APPLIANCES AND INJECTION MOLDED ARTICLES OR FILMS | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-01-16 | — | — | US | disclosed |
| EP-0659801-A1 | Polyimide | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1995-06-28 | — | — | EP | disclosed |