SCHEMBL25906221

SCHEMBL25906221

Oc1ccc2c(oc3c(C(F)(F)F)c(O)ccc32)c1C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATP1A1 P05023 2/20 0.41
ATP1B1 P05026 2/20 0.41
ATP1A3 P13637 2/20 0.41
ATP1B2 P14415 2/20 0.41
ATP1A2 P50993 2/20 0.41
ATP1B3 P54709 2/20 0.41
FXYD2 P54710 2/20 0.41
ATP1A4 Q13733 2/20 0.41
NUDT1 P36639 1/20 0.41
CSNK2A1 P68400 2/20 0.40
CSNK2A2 P19784 1/20 0.40
CSNK2B P67870 1/20 0.40
ESR2 Q92731 9/20 0.35
PKLR P30613 1/20 0.35
GALNT2 Q10471 1/20 0.35
GALNT1 Q10472 1/20 0.35
GALNT3 Q14435 1/20 0.35
GALNT10 Q86SR1 1/20 0.35
GALNT13 Q8IUC8 1/20 0.35
GALNT6 Q8NCL4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5146822 0.75 NQO2 (0.37) ESR2ESR1PIK3CAHSD17B1HSD17B2
SCHEMBL25878374 0.74 CYP1A1 (0.33)
SCHEMBL19444022 0.71 ESR1 (0.46) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL19443971 0.70 ESR2 (0.58) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL25871161 0.70 HSD17B1 (0.32) CSNK2A1CSNK2A2CSNK2BHSD17B1HSD17B2
SCHEMBL25906282 0.69 MAOA (0.38) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL3874869 0.69 ATP1A1 (0.74) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL27846971 0.69 PIM1 (0.36) ESR2PIK3CA
SCHEMBL25878528 0.67 ESR1 (0.33) ESR2ESR1
SCHEMBL5512574 0.66 TDP1 (0.45) PIK3CAHSD17B1HSD17B2AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134595-A1 POLYMERIZABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed