Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954506 | 0.77 | LIPG (0.40) | LIPG | |
| SCHEMBL18706647 | 0.77 | LIPG (0.40) | LIPG | |
| SCHEMBL17236536 | 0.77 | LIPG (0.40) | LIPG | |
| SCHEMBL15536431 | 0.77 | GABRA1 (0.46) | LIPGMAPT | |
| SCHEMBL9939108 | 0.77 | LIPG (0.40) | LIPG | |
| Hydrochloric Acid SCHEMBL16396387 | 0.76 | F11 (0.41) | LIPG | |
| SCHEMBL29955435 | 0.75 | ALDH1A1 (0.56) | ALDH1A1 | |
| SCHEMBL1994576 | 0.75 | ALDH1A1 (0.56) | ALDH1A1 | |
| SCHEMBL25745449 | 0.73 | ENPP2 (0.42) | LIPGMAPT | |
| SCHEMBL13781687 | 0.71 | HTR2A (0.51) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708347-B2 | Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 2023-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708347-B2 | Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors | C9, C5, C1QBP | LIPG 1355/4885P2RX7 1134/4885SCN8A 4587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.