SCHEMBL258838

SCHEMBL258838

Brc1ccc2c(c1)sc1ccccc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.61
ALDH1A1 P00352 4/20 0.59
MAPT P10636 4/20 0.59
RAB9A P51151 2/20 0.59
HPGD P15428 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
IDO1 P14902 1/20 0.43
TDO2 P48775 1/20 0.42
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
POLB P06746 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KDM4E B2RXH2 2/20 0.39
EPM2A O95278 1/20 0.39
PTPN2 P17706 1/20 0.39
PTPN1 P18031 1/20 0.39
PTPN22 Q9Y2R2 1/20 0.39
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29601409 1.00 GPR3 (0.61) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL29887048 1.00 GPR3 (0.61) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL29644557 0.89 RAB9A (0.41) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL205544 0.89 RAB9A (0.41) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL490641 0.88 KDM4E (0.54) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL29499025 0.88 MAPT (0.46) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL17037087 0.88 MAPT (0.46) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL29536667 0.87 GPR3 (0.61) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL26685 0.87 GPR3 (0.61) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL14603416 0.87 MAPT (0.50) GPR3ALDH1A1MAPTRAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 586 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114163417-B Synthesis method of 3-bromodibenzothiophene 郑州海阔光电材料有限公司 2023-08-04 CN claimed
CN-114773313-A Preparation method of dibenzothiophene derivative and dibenzothiophene derivative 陕西维世诺新材料有限公司 2022-07-22 CN claimed
CN-114163417-A Synthetic method of 3-bromodibenzothiophene 郑州海阔光电材料有限公司 2022-03-11 CN claimed
CN-101712674-A Alkyl substituted-S,S-dioxo-dibenzothiophene monomer, preparation method and polymer thereof UNIV SOUTH CHINA TECH 2010-05-26 CN claimed
CN-116813860-B Method for preparing polyurethane catalyst for rubber roller by taking camphene as starting material 沈阳东阳聚氨酯有限公司 2026-05-15 CN disclosed
CN-122010983-A Compound, material for organic electroluminescent element, and electronic device 出光兴产株式会社 2026-05-12 CN disclosed
US-20260123273-A1 TRIPHENYLENE-TRIAZINE-DIBENZOFURAN/DIBENZOTHIOPHENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2026-04-30 US disclosed
EP-4441048-B1 TRIPHENYLENE-TRIAZINE-DIBENZOFURANE/DIBENZOTHIOPHENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2026-04-22 EP disclosed
US-12538704-B2 4H-imidazo[1,2-a]imidazoles for electronic applications UDC IRELAND LIMITED (IE) 2026-01-27 US disclosed
US-12503472-B2 Compound for organic electric element, organic electric element using the same, and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2025-12-23 US disclosed
US-20250386727-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2025-12-18 US disclosed
US-20250346585-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2025-11-13 US disclosed
US-6849202-B2 COMPOUND HAVING PHENYLACETYLENE STRUCTURE, LIQUID CRYSTAL COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC PRODUCT, OPTICAL OR LIQUID CRYSTAL ELEMENT, DIBENZOTHIOPHENE COMPOUND, INTERMEDIATE, AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-02-01 US disclosed
US-20040232384-A1 Compound having phenylacetylene structure, liquid crystal composition, polymer, optically anisotropic product, optical or liquid crystal element, dibenzothiophene compound, intermediate, and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED 2004-11-25 US disclosed
US-20020110650-A1 Compound having phenylacetylene structure, liquid crystal composition, polymer, optically anisotropic product, optical or liquid crystal element, dibenzothiophene compound, intermediate, and process for producing the same SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2002-08-15 US disclosed
US-5132420-A INTERMEDIATES FOR PREPARING 2-(SUBSTITUTED-DIBENZO-FURANYL AND DIBENZOTHIENYL) CARBAPENEM ANTIBACTERIAL AGENTS MERCK & CO., INC. (US) 1992-07-21 US disclosed
EP-0480715-A1 Intermediates for preparing 2-(substituted-dibenzofuranyl and dibenzothienyl) carbapenem antibacterial agents MERCK & CO. INC. (US) 1992-04-15 EP disclosed
EP-0444889-A1 Novel synthesis of carbapenem intermediates MERCK & CO. INC. (US) 1991-09-04 EP disclosed
US-5025008-A For methicillin resistant Staphylococcus aureus MERCK & CO., INC. (US) 1991-06-18 US disclosed
EP-0405774-A1 2-(substituted-dibenzofuranyl and dibenzothienyl)carbapenem antibacterial agents MERCK & CO. INC. (US) 1991-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12538704-B2 4H-imidazo[1,2-a]imidazoles for electronic applications RIF1, NR2E1, NR3C1 GPR3 1454/4885ALDH1A1 680/4885MAPT 4314/4885
US-20040232384-A1 Compound having phenylacetylene structure, liquid crystal composition, polymer, optically anisotropic product, optical or liquid crystal element, dibenzothiophene compound, intermediate, and process for producing the same CCNT1, BPNT1, PEAK1 GPR3 2817/4885ALDH1A1 50/4885MAPT 115/4885
US-20250346585-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS C5, C1S, C9 GPR3 2917/4885ALDH1A1 1707/4885MAPT 1464/4885
US-20260123273-A1 TRIPHENYLENE-TRIAZINE-DIBENZOFURAN/DIBENZOTHIOPHENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES OCIAD1, OCIAD2, POU5F1 GPR3 1817/4885ALDH1A1 527/4885MAPT 1615/4885
US-12503472-B2 Compound for organic electric element, organic electric element using the same, and electronic device thereof PIEZO1, ORAI2, OR10J3 GPR3 4638/4885ALDH1A1 3927/4885MAPT 1784/4885
US-20020110650-A1 Compound having phenylacetylene structure, liquid crystal composition, polymer, optically anisotropic product, optical or liquid crystal element, dibenzothiophene compound, intermediate, and process for producing the same CCNT1, NAT1, PEAK1 GPR3 2764/4885ALDH1A1 37/4885MAPT 57/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.