Sugi Predict

Sugi Predict / Compounds / SCHEMBL490641

SCHEMBL490641

SCHEMBL490641

O=c1c2ccccc2sc2cc(Br)ccc12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.54
▸ ALDH1A1 P00352 8/20 0.50
▸ MAPT P10636 7/20 0.50
▸ RAB9A P51151 4/20 0.50
▸ L3MBTL1 Q9Y468 3/20 0.50
▸ NPC1 O15118 3/20 0.50
▸ TDP1 Q9NUW8 2/20 0.50
▸ HPGD P15428 3/20 0.47
▸ SMN1; SMN2 Q16637 2/20 0.47
▸ GPR3 P46089 1/20 0.46
▸ MAOA P21397 2/20 0.46
▸ MAOB P27338 2/20 0.46
▸ POLB P06746 3/20 0.44
▸ HCRTR1 O43613 2/20 0.44
▸ LMNA P02545 1/20 0.44
▸ MEN1 O00255 2/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ GAA P10253 1/20 0.43
▸ ALOX15 P16050 1/20 0.42
▸ NFKB1 P19838 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5019819 0.90 HSP90AA1 (0.43) KDM4EALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL30923497 0.90 HSP90AA1 (0.43) KDM4EALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL1615357 0.89 KDM4E (0.64) KDM4EALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL29887048 0.88 GPR3 (0.61) KDM4EALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL29601409 0.88 GPR3 (0.61) KDM4EALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL258838 0.88 GPR3 (0.61) KDM4EALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL18261966 0.87 KDM4E (0.47) KDM4EALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL30593470 0.87 KDM4E (0.47) KDM4EALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL22337262 0.84 KDM4E (0.43) KDM4EALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL13135131 0.82 ALDH1A1 (0.49) KDM4EALDH1A1MAPTRAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111018882-B Spiro-based dithiane micromolecule hole transport material and preparation method and application thereof 华南协同创新研究院 2021-03-16 — — CN claimed
CN-111018882-A Spiro-based dithiane micromolecule hole transport material and preparation method and application thereof 华南协同创新研究院 2020-04-17 — — CN claimed
US-11812660-B2 Organic compound, electroluminescent material and application thereof WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2023-11-07 — — US disclosed
US-11812660-B2 Organic compound, electroluminescent material and application thereof WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2023-11-07 — — US disclosed
US-11450821-B2 Organic electroluminescence device and polycyclic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2022-09-20 — — US disclosed
US-20220144857-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2022-05-12 — — US disclosed
EP-3995497-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE Canon Kabushiki Kaisha (JP) 2022-05-11 — — EP disclosed
WO-2021215782-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 솔루스첨단소재 주식회사 (KR) 2021-10-28 — — WO disclosed
WO-2021215782-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 솔루스첨단소재 주식회사 (KR) 2021-10-28 — — WO disclosed
CN-111018882-B Spiro-based dithiane micromolecule hole transport material and preparation method and application thereof 华南协同创新研究院 2021-03-16 — — CN disclosed
US-20210066620-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-03-04 — — US disclosed
US-7553850-B2 Tricyclic-bridged piperidinylidene derivatives as δ-opioid modulators JANSSEN PHARMACEUTICA NV (BG) 2009-06-30 — — US disclosed
EP-1910353-A1 TRICYCLIC DELTA- OPIOID MODULATORS JANSSEN PHARMACEUTICA N.V. (BE) 2008-04-16 — — EP disclosed
WO-2007030089-A1 TRICYCLIC DELTA- OPIOID MODULATORS JANSSEN PHARMACEUTICA N.V. (BE) 2007-03-15 — — WO disclosed
CN-1839135-A Tricyclic delta-opioid modulators JANSSEN PHARMACEUTICA NV (BE) 2006-09-27 — — CN disclosed
EP-1644373-A1 TRICYCLIC DELTA OPIOID MODULATORS JANSSEN PHARMACEUTICA N.V. (BE) 2006-04-12 — — EP disclosed
US-20060030585-A1 Tricyclic delta-opioid modulators JANSSEN PHARMACEUTICA N.V. (BE) 2006-02-09 — — US disclosed
WO-2005003131-A1 TRICYCLIC DELTA OPIOID MODULATORS JANSSEN PHARMACEUTICA N.V. (BE) 2005-01-13 — — WO disclosed
US-20050009860-A1 Tricyclic delta-opioid modulators JANSSEN PHARMACEUTICA, N.V. (BE) 2005-01-13 — — US disclosed
EP-0441221-A1 Method for preventing the appearance of efflorescence of mineral substrates BASF Aktiengesellschaft (DE) 1991-08-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11812660-B2 Organic compound, electroluminescent material and application thereof MRPS22, RPS3A, MRPS23 KDM4E 3223/4885ALDH1A1 2134/4885MAPT 4533/4885
US-20220144857-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE SPIN4, OR10J3, SPIN1 KDM4E 1793/4885ALDH1A1 601/4885MAPT 2167/4885
US-20050009860-A1 Tricyclic delta-opioid modulators OPRD1, OPRK1, OPRL1 KDM4E 2174/4885ALDH1A1 1302/4885MAPT 1156/4885
US-20060030585-A1 Tricyclic delta-opioid modulators OPRD1, OPRK1, OPRL1 KDM4E 2174/4885ALDH1A1 1302/4885MAPT 1156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.