SCHEMBL25890274

SCHEMBL25890274

CO/N=C(/c1cccc(OCc2ccc3ccccc3c2)c1)C1CCOCC1

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 13/20 0.51
F2 P00734 2/20 0.45
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9308093 0.83 MRGPRX4 (0.51) ALOX5F2ALDH1A1
SCHEMBL9308170 0.71 ALOX5 (0.52) ALOX5F2
SCHEMBL8953777 0.71 MAOB (0.43) ALDH1A1
SCHEMBL8953702 0.71 MAOB (0.43) ALDH1A1
SCHEMBL9307254 0.71 ALOX5 (0.64) ALOX5ALDH1A1
SCHEMBL9308680 0.70 ALOX5 (0.52) ALOX5
SCHEMBL9186121 0.70 MAOB (0.74) F2
SCHEMBL4638462 0.70 F2 (0.68) F2
SCHEMBL25890731 0.69 ALOX5 (0.51) ALOX5
SCHEMBL9577709 0.69 MRGPRX4 (0.55) F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3877372-B1 ENANTIOSELECTIVE REDUCTION OF OXIME-DERIVATIVES INVOLVING IRIDIUM BASED CATALYSTS SYNGENTA CROP PROTECTION AG (CH) 2023-08-02 EP disclosed