SCHEMBL28050335

SCHEMBL28050335

CO/N=C1\c2ccccc2COC1C=O

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.34
MAOA P21397 1/20 0.34
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
GAA P10253 2/20 0.33
MAPT P10636 2/20 0.33
NPC1 O15118 1/20 0.33
HPGD P15428 1/20 0.33
ALOX12 P18054 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ACHE P22303 1/20 0.32
MIF P14174 1/20 0.32
LMNA P02545 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27866565 1.00 MAOB (0.34) MAOBMAOAKDM4EALDH1A1GAA
SCHEMBL27849620 0.81 MAOA (0.37) MAOBMAOAALDH1A1MAPTHPGD
SCHEMBL28769668 0.72 MAOA (0.40) MAOBMAOAALDH1A1MAPTNPC1
SCHEMBL25890369 0.70 ACHE (0.50) ACHELMNA
SCHEMBL2653892 0.68 SLC6A2 (0.34) MAOBMAOANPC1RAB9ASMN1; SMN2
SCHEMBL25890363 0.67 RAB9A (0.36) KDM4EALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL11372112 0.66 MAOA (0.48) MAOBMAOAKDM4EALDH1A1GAA
SCHEMBL27754818 0.66 SLC6A2 (0.33) MAOBMAOANPC1RAB9ASMN1; SMN2
SCHEMBL29765453 0.65 MAOA (0.56) MAOBMAOAKDM4EALDH1A1GAA
SCHEMBL3628522 0.65 MAOA (0.56) MAOBMAOAKDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114685313-A Preparation method of trifloxystrobin 南通泰禾化工股份有限公司 2022-07-01 CN disclosed
CN-105294490-A Trifloxystrobin synthesizing method JIANGSU CHANGQING AGROCHEMICAL CO LTD 2016-02-03 CN disclosed