Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.87 |
| ▸ | MTHFD1 | P11586 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.66 |
| ▸ | MTHFD2 | P13995 | 3/20 | 0.61 |
| ▸ | FPGS | Q05932 | 2/20 | 0.59 |
| ▸ | TYMS | P04818 | 1/20 | 0.55 |
| ▸ | GART | P22102 | 5/20 | 0.54 |
| ▸ | ATIC | P31939 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13418314 | 1.00 | DHFR (0.87) | DHFRMTHFD1LMNASOSTMTHFD2 | |
| SCHEMBL29616604 | 1.00 | DHFR (0.87) | DHFRMTHFD1LMNASOSTMTHFD2 | |
| SCHEMBL188064 | 1.00 | DHFR (0.87) | DHFRMTHFD1LMNASOSTMTHFD2 | |
| SCHEMBL3181068 | 1.00 | DHFR (0.87) | DHFRMTHFD1LMNASOSTMTHFD2 | |
| Leucovorin SCHEMBL3031362 | 0.93 | DHFR (1.00) | DHFRMTHFD1LMNASOSTMTHFD2 | |
| Folinic Acid SCHEMBL29616563 | 0.93 | DHFR (1.00) | DHFRMTHFD1LMNASOSTMTHFD2 | |
| Folinic Acid SCHEMBL21498299 | 0.93 | DHFR (1.00) | DHFRMTHFD1LMNASOSTMTHFD2 | |
| Leucovorin SCHEMBL29385578 | 0.93 | DHFR (1.00) | DHFRMTHFD1LMNASOSTMTHFD2 | |
| Leucovorin SCHEMBL36113 | 0.93 | DHFR (1.00) | DHFRMTHFD1LMNASOSTMTHFD2 | |
| Leucovorin SCHEMBL29379632 | 0.93 | DHFR (1.00) | DHFRMTHFD1LMNASOSTMTHFD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 411 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12318395-B2 | Ethinyl estradiol-β-cyclodextrin complex and process for preparing thereof | LABORATORIOS LEON FARMA, S.A. (ES) | 2025-06-03 | — | — | US | claimed |
| US-20220279831-A1 | COMPOSITIONS, KITS AND METHODS FOR NUTRITION SUPPLEMENTATION | EXELTIS FRANCE (FR) | 2022-09-08 | — | — | US | claimed |
| WO-2020120548-A1 | ETHINYL ESTRADIOL-β-CYCLODEXTRIN COMPLEX AND PROCESS FOR PREPARING THEREOF | LABORATORIOS LEON FARMA, S.A. (ES) | 2020-06-18 | — | — | WO | claimed |
| EP-3666260-A1 | ETHINYL ESTRADIOL-BETA-CYCLODEXTRIN COMPLEX AND PROCESS FOR PREPARING THEREOF | Laboratorios Leon Farma SA (ES) | 2020-06-17 | — | — | EP | claimed |
| EP-3512507-A1 | ORAL MEDICATION FORMULATIONS | Grunbiotics Pty Ltd (AU) | 2019-07-24 | — | — | EP | claimed |
| US-10265343-B2 | Kits and methods for nutrition supplementation | EXELTIS USA, INC. (US) | 2019-04-23 | — | — | US | claimed |
| US-10201560-B2 | Compositions and methods for nutrition supplementation | EXELTIS USA, INC. (US) | 2019-02-12 | — | — | US | claimed |
| US-20180256582-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF METABOLIC DISORDERS | BIOMARIN PHARMACEUTICAL INC. | 2018-09-13 | — | — | US | claimed |
| WO-2018071988-A1 | ORAL MEDICATION FORMULATIONS | Grunbiotics Pty Ltd (AU) | 2018-04-26 | — | — | WO | claimed |
| US-20170202802-A1 | COMPOSITIONS, KITS AND METHODS FOR NUTRITION SUPPLEMENTATION | EXELTIS USA, INC. | 2017-07-20 | — | — | US | claimed |
| US-6451360-B2 | WITH NATURAL ISOMERS OF REDUCED FOLATE SUCH AS 5-METHYL-6(S)-TETRAHYDROFOLIC ACID, A FOOD PREPARATION, AND/OR ESSENTIAL NUTRIENT PREPARATION (OTHER THAN ASCORBIC ACID) IN GIVEN MOLAR AMOUNTS | SOUTH ALABAMA MEDICAL SCIENCE FOUNDATION | 2002-09-17 | — | — | US | claimed |
| US-20020094970-A1 | Compositions and methods for treating an arthritic condition | TUFTS UNIVERSITY | 2002-07-18 | — | — | US | claimed |
| US-20010046533-A1 | METHOD FOR TREATING A SUBJECT AFFLICTED WITH INTESTINAL MALABSORPTION | SOUTH ALABAMA MEDICAL SCIENCE FOUNDATION | 2001-11-29 | — | — | US | claimed |
| US-6254904-B1 | COMPRISING: (6S)-TETRAHYDROFOLIC ACID AND DERIVATIVES AND POLYGLUTAMYL DERIVATIVES; MULTIVITAMIN BREAKFAST FOODS, INFANT FORMULAS, DIETARY SUPPLEMENTS AND ANIMAL FEED PREPARATION | SOUTH ALABAMA MEDICAL SCIENCE FOUNDATION | 2001-07-03 | — | — | US | claimed |
| US-6011040-A | Use of tetrahydrofolates in natural stereoisomeric form for the production of a pharmaceutical preparation suitable for influencing the homocysteine level, particularly for assisting the remethylation of homocysteine | EPROVA AG (CH) | 2000-01-04 | — | — | US | claimed |
| US-5997915-A | NATURAL ISOMERS OF TETRAHYDROFOLIC ACID DERIVATIVES | SOUTH ALABAMA MEDICAL SCIENCE FOUNDATION (US) | 1999-12-07 | — | — | US | claimed |
| EP-0877563-A4 | FOOD AND VITAMIN PREPARATIONS CONTAINING THE NATURAL ISOMER OF REDUCED FOLATES | UNIV SOUTH ALABAMA (US) | 1999-06-09 | — | — | EP | claimed |
| EP-0898965-A2 | Use of tetrahydrofolates for modulating the homocysteine level | EPROVA Aktiengesellschaft (CH) | 1999-03-03 | — | — | EP | claimed |
| EP-0877563-A1 | FOOD AND VITAMIN PREPARATIONS CONTAINING THE NATURAL ISOMER OF REDUCED FOLATES | South Alabama Medical Science Foundation (US) | 1998-11-18 | — | — | EP | claimed |
| WO-1997027764-A1 | FOOD AND VITAMIN PREPARATIONS CONTAINING THE NATURAL ISOMER OF REDUCED FOLATES | SOUTH ALABAMA MEDICAL SCIENCE FOUNDATION (US) | 1997-08-07 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180256582-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF METABOLIC DISORDERS | PAH, BHMT, FAH | DHFR 33/4885MTHFD1 70/4885LMNA 2945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.