Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 3/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25891804 | 1.00 | LMNA (0.48) | LMNATMEM97SIGMAR1TDP1ALDH1A1 | |
| SCHEMBL18288401 | 1.00 | LMNA (0.48) | LMNATMEM97SIGMAR1TDP1ALDH1A1 | |
| SCHEMBL2493185 | 0.86 | ALDH1A1 (0.52) | TMEM97SIGMAR1ALDH1A1NPC1 | |
| SCHEMBL6933031 | 0.86 | ALDH1A1 (0.52) | TMEM97SIGMAR1ALDH1A1NPC1 | |
| SCHEMBL9098184 | 0.86 | ALDH1A1 (0.52) | TMEM97SIGMAR1ALDH1A1NPC1 | |
| SCHEMBL17888100 | 0.80 | TBXA2R (0.43) | LMNATMEM97SIGMAR1ALDH1A1NAMPT | |
| SCHEMBL25417926 | 0.80 | TMEM97 (0.49) | LMNATMEM97SIGMAR1TDP1NAMPT | |
| SCHEMBL19136746 | 0.80 | KMT2A (0.49) | LMNATMEM97SIGMAR1ALDH1A1NPC1 | |
| SCHEMBL4361938 | 0.78 | CA2 (0.45) | TMEM97SIGMAR1ALDH1A1HTR1ANAMPT | |
| SCHEMBL17830008 | 0.78 | HTR7 (0.47) | TMEM97SIGMAR1ALDH1A1NPC1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242480-A1 | Alkyne Compound, Vitamin D Compound, Analytical Method, and Production Method | JEOL LTD. (JP) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242480-A1 | Alkyne Compound, Vitamin D Compound, Analytical Method, and Production Method | VDR, CYP2R1, CYP24A1 | LMNA 1250/4885TMEM97 3274/4885SIGMAR1 1995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.