Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1652005 | 0.85 | CYP2C9 (0.37) | PBRM1ALDH1A1CYP2C9HSD17B1KDM4E | |
| SCHEMBL13930558 | 0.82 | ALDH1A1 (0.35) | PBRM1ALDH1A1KDM4EHPGDRXRA | |
| SCHEMBL17060104 | 0.77 | CYP1A2 (0.35) | ALDH1A1KDM4EHPGDGAATYMS | |
| SCHEMBL30067255 | 0.74 | PBRM1 (0.46) | PBRM1ALDH1A1CYP2C9HSD17B1KDM4E | |
| SCHEMBL7998384 | 0.74 | PBRM1 (0.37) | PBRM1ALDH1A1CYP2C9HSD17B1KDM4E | |
| SCHEMBL833981 | 0.74 | ALDH1A1 (0.44) | PBRM1ALDH1A1HSD17B1KDM4EHPGD | |
| SCHEMBL30777430 | 0.74 | ALDH1A1 (0.44) | PBRM1ALDH1A1HSD17B1KDM4EHPGD | |
| SCHEMBL25119189 | 0.74 | UPP1 (0.39) | PBRM1ALDH1A1CYP2C9KDM4EHPGD | |
| SCHEMBL7123504 | 0.73 | ALDH1A1 (0.33) | ALDH1A1KDM4EHPGDTYMSMAPT | |
| SCHEMBL31674224 | 0.73 | HSD17B1 (0.39) | PBRM1HSD17B1MAOAMAOBPRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242473-A1 | THYROMIMETICS | AUTOBAHN THERAPEUTICS, INC. | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242473-A1 | THYROMIMETICS | TPO, THOP1, THRB | PBRM1 4681/4885ALDH1A1 1619/4885CYP2C9 3861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.