Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 6/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 3/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15769035 | 0.89 | FPR2 (0.45) | USP30GPR119RORC | |
| SCHEMBL25899022 | 0.87 | GPR119 (0.42) | USP30GPR119HPGDS | |
| SCHEMBL15781327 | 0.87 | USP30 (0.40) | USP30GPR119RORC | |
| SCHEMBL25898964 | 0.86 | DDB1 (0.44) | USP30 | |
| SCHEMBL25899064 | 0.84 | LIPE (0.42) | USP30GPR119 | |
| SCHEMBL25898943 | 0.82 | GPR119 (0.53) | GPR119KDM4EPKM | |
| SCHEMBL15781353 | 0.81 | RORC (0.44) | USP30GPR119RORC | |
| SCHEMBL18325517 | 0.81 | USP30 (0.52) | USP30GPR119HPGDSJAK2JAK1 | |
| SCHEMBL15781325 | 0.80 | DDB1 (0.41) | USP30GPR119RORC | |
| SCHEMBL29960225 | 0.80 | RORC (0.47) | USP30GPR119HPGDSJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114858-A1 | BENZOFURAN AND BENZOTHIOPHENE PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |