Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25898964 | 0.89 | DDB1 (0.44) | USP30MMP1MMP9MMP13 | |
| SCHEMBL25899022 | 0.86 | GPR119 (0.42) | GPR119USP30 | |
| SCHEMBL25899063 | 0.86 | GPR119 (0.45) | LIPEGPR119NOTUMMGLLKCNH2 | |
| SCHEMBL15781327 | 0.84 | USP30 (0.40) | GPR119USP30MMP1MMP9MMP13 | |
| SCHEMBL25898944 | 0.84 | USP30 (0.44) | GPR119USP30 | |
| SCHEMBL1810911 | 0.80 | GPR119 (0.50) | LIPEGPR119NOTUMMGLLKCNH2 | |
| SCHEMBL15781325 | 0.78 | DDB1 (0.41) | GPR119USP30 | |
| SCHEMBL15769035 | 0.78 | FPR2 (0.45) | GPR119USP30MMP1MMP9MMP13 | |
| SCHEMBL30898354 | 0.75 | ABHD6 (0.53) | LIPEGPR119ABHD6NOTUMMGLL | |
| SCHEMBL30409654 | 0.75 | ABHD6 (0.53) | LIPEGPR119ABHD6NOTUMMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114858-A1 | BENZOFURAN AND BENZOTHIOPHENE PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |