Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25924607 | 0.77 | — | — | |
| SCHEMBL25924619 | 0.68 | IDO1 (0.38) | IDO1CYP2C9KCNH2 | |
| SCHEMBL25924494 | 0.65 | IDO1 (0.37) | IDO1CYP2C9KCNH2 | |
| SCHEMBL25318420 | 0.64 | MAP3K12 (0.32) | — | |
| SCHEMBL30506911 | 0.64 | MAP3K12 (0.32) | — | |
| SCHEMBL25924578 | 0.64 | MAP3K12 (0.32) | — | |
| SCHEMBL16428243 | 0.64 | NQO2 (0.37) | — | |
| SCHEMBL31349463 | 0.64 | OPRM1 (0.31) | — | |
| SCHEMBL25924927 | 0.62 | PRPS1 (0.44) | IDO1CYP2C9KCNH2 | |
| SCHEMBL17041972 | 0.62 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |