Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL337270 | 0.97 | LMNA (0.57) | LMNACYP2A6CYP1A2IDO1TSHR | |
| Ammonia Solution, Strong SCHEMBL2467561 | 0.93 | LMNA (0.53) | LMNACYP2A6CYP1A2IDO1TSHR | |
| SCHEMBL2056633 | 0.93 | LMNA (0.53) | LMNACYP2A6CYP1A2IDO1TSHR | |
| SCHEMBL7146462 | 0.93 | LMNA (0.53) | LMNACYP2A6CYP1A2IDO1TSHR | |
| Silver SCHEMBL9414198 | 0.93 | LMNA (0.53) | LMNACYP2A6CYP1A2IDO1TSHR | |
| SCHEMBL25280488 | 0.93 | LMNA (0.53) | LMNACYP2A6CYP1A2IDO1TSHR | |
| SCHEMBL5167685 | 0.93 | LMNA (0.53) | LMNACYP2A6CYP1A2IDO1TSHR | |
| Potassium SCHEMBL31218525 | 0.90 | LMNA (0.50) | LMNACYP2A6CYP1A2IDO1TSHR | |
| Silver SCHEMBL9414202 | 0.90 | LMNA (0.50) | LMNACYP2A6CYP1A2IDO1TSHR | |
| SCHEMBL5972567 | 0.85 | CYP1A2 (0.57) | LMNACYP2A6CYP1A2IDO1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 526 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747611-A1 | OPTICAL ELECTRODE ANALYTE DETECTION SYSTEM AND METHODS OF USE | Vital Biosciences Inc. (CA) | 2026-05-27 | — | — | EP | claimed |
| US-12601705-B2 | Sensor for measuring ionized magnesium | INSTRUMENTATION LABORATORY COMPANY (US) | 2026-04-14 | — | — | US | claimed |
| EP-4476537-B1 | SENSOR FOR MEASURING IONIZED MAGNESIUM | INSTR LABORATORY CO (US) | 2025-10-29 | — | — | EP | claimed |
| EP-4580489-A1 | DEVICES AND METHODS FOR MEASURING A CONCENTRATION OF A TARGET ANALYTE IN A BIOLOGICAL FLUID IN VIVO | DexCom, Inc. (US) | 2025-07-09 | — | — | EP | claimed |
| EP-4321860-B1 | IMPROVED MAGNESIUM ION SELECTIVE MEMBRANES | SIEMENS HEALTHCARE DIAGNOSTICS INC (US) | 2025-07-09 | — | — | EP | claimed |
| EP-3622280-B1 | POTENTIOMETRIC ION SELECTIVE ELECTRODE WITH AN INTERNAL ELECTROLYTE LAYER COMPRISING CARBON PASTE | SIEMENS HEALTHCARE DIAGNOSTICS INC (US) | 2025-06-25 | — | — | EP | claimed |
| US-12222310-B2 | Magnesium ion selective membranes | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2025-02-11 | — | — | US | claimed |
| WO-2025022286-A1 | OPTICAL ELECTRODE ANALYTE DETECTION SYSTEM AND METHODS OF USE | VITAL BIOSCIENCES INC. (CA) | 2025-01-30 | — | — | WO | claimed |
| EP-4476537-A1 | SENSOR FOR MEASURING IONIZED MAGNESIUM | Instrumentation Laboratory Company (US) | 2024-12-18 | — | — | EP | claimed |
| EP-4453550-A1 | POTASSIUM SENSOR MEMBRANE COMPOSITION | Proton Intelligence Inc. (CA) | 2024-10-30 | — | — | EP | claimed |
| WO-2001073425-A2 | LITHIUM ION-SELECTIVE ELECTRODE FOR CLINICAL APPLICATIONS | BECKMAN COULTER, INC. (US) | 2001-10-04 | — | — | WO | claimed |
| US-5863972-A | POLYUREAURETHANE COPOLYMERS AND NONIONIC IONOPHORES WITH CALCIUM ION | CHIRON DIAGNOSTICS CORPORATION (US) | 1999-01-26 | — | — | US | claimed |
| EP-0827589-A1 | ALL-SOLID STATE REFERENCE ELECTRODE | Sinvent AS (NO) | 1998-03-11 | — | — | EP | claimed |
| EP-0792454-A1 | RANDOMLY SEGMENTED THERMOPLASTIC POLYURETHANES AS MATRIX FOR ELECTROCHEMICAL ANALYSIS OF Ca?++ IONS | Chiron Diagnostics Corporation (US) | 1997-09-03 | — | — | EP | claimed |
| WO-1996035116-A1 | ALL-SOLID STATE REFERENCE ELECTRODE | SINVENT AS (NO) | 1996-11-07 | — | — | WO | claimed |
| WO-1996015443-A1 | RANDOMLY SEGMENTED THERMOPLASTIC POLYURETHANES AS MATRIX FOR ELECTROCHEMICAL ANALYSIS OF Ca++ IONS | CHIRON DIAGNOSTICS CORPORATION_ (CH) | 1996-05-23 | — | — | WO | claimed |
| US-5192417-A | Manic depression | TERUMO KABUSHIKI KAISHA (JP) | 1993-03-09 | — | — | US | claimed |
| EP-0186210-B1 | Ion sensor | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1992-04-22 | — | — | EP | claimed |
| EP-0174572-B1 | CYCLOHEXANE-1,2-DICARBOXYLIC AMIDES, IONIC-SELECTIVES MEMBRANES AND TEST APPARATUS CONTAINING THESE COMPOUNDS | Willi Möller AG (CH) | 1991-03-06 | — | — | EP | claimed |
| US-4770759-A | DIALKYL PHTHALATE OR PHENYL ETHER PLASTICIZER | NOVA BIOMEDICAL CORPORATION (US) | 1988-09-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12601705-B2 | Sensor for measuring ionized magnesium | MAG, S100B, S100P | LMNA 1697/4885CYP2A6 1058/4885CYP1A2 4084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.