SCHEMBL259273

SCHEMBL259273

C=CS(=O)(=O)CC(=O)NCCNC(=O)CS(=O)(=O)C=C

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
MAPT P10636 1/20 0.31
ALDH1A1 P00352 3/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethane SCHEMBL2815456 0.96 ALDH1A1 (0.32) ALDH1A1MEN1KMT2A
SCHEMBL1335532 0.94
Propane SCHEMBL6761944 0.94 MEN1 (0.35) TSHRALDH1A1MEN1KMT2A
SCHEMBL5145542 0.91 SMN1; SMN2 (0.37) TSHRSMN1; SMN2MAPTALDH1A1MEN1
SCHEMBL13042486 0.91 SMN1; SMN2 (0.41) TSHRSMN1; SMN2MAPTALDH1A1MAPK1
SCHEMBL17617949 0.90
SCHEMBL13042487 0.90 SMN1; SMN2 (0.45) TSHRSMN1; SMN2MAPTALDH1A1MAPK1
SCHEMBL28452262 0.88 ALDH1A1 (0.34) TSHRSMN1; SMN2ALDH1A1
SCHEMBL20233447 0.87
SCHEMBL28065030 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1675 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115368056-A Crystal nucleus enhanced liquid alkali-free accelerator and preparation method and application thereof 河北三楷深发科技股份有限公司 2022-11-22 CN claimed
CN-115368514-A Dispersing agent for crystal nucleus type early strength agent, crystal nucleus type early strength agent and preparation method 河北三楷深发科技股份有限公司 2022-11-22 CN claimed
US-11197887-B2 Proton-binding polymers for oral administration TRICIDA, INC. (US) 2021-12-14 US claimed
EP-3219312-B1 ION BINDING POLYMERS AND USES THEREOF RELYPSA INC (US) 2019-01-30 EP claimed
EP-3219312-A1 ION BINDING POLYMERS AND USES THEREOF Relypsa, Inc. (US) 2017-09-20 EP claimed
US-8889115-B2 Ion binding polymers and uses thereof RELYPSA, INC. (US) 2014-11-18 US claimed
US-20140286891-A1 ION BINDING POLYMERS AND USES THEREOF ILYPSA, INC. 2014-09-25 US claimed
US-8778324-B2 Ion binding polymers and uses thereof RELYPSA, INC. (US) 2014-07-15 US claimed
EP-2269589-B1 Ion binding polymers and uses thereof RELYPSA INC (US) 2013-12-25 EP claimed
US-20130272991-A1 ION BINDING POLYMERS AND USES THEREOF VIFOR (INTERNATIONAL) LTD. (CH) 2013-10-17 US claimed
EP-0736801-B1 Molecular grafting to energetically treated polyesters to promote adhesion of gelatin-containing layers EASTMAN KODAK CO (US) 2004-02-18 EP claimed
US-20030186811-A1 Recording material FUJI PHOTO FILM CO., LTD. 2003-10-02 US claimed
EP-0785466-B1 Molecular grafting of hardener/gelatin blends to energetically treated polyesters to promote adhesion of layers EASTMAN KODAK CO (US) 2003-09-03 EP claimed
EP-0929530-B1 QUINAZOLINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ASTRAZENECA AB (SE) 2002-11-20 EP claimed
US-5968646-A Molecular grafting of hardener/gelatin blends to energetically treated polyesters to promote adhesion of layers EASTMAN KODAK COMPANY (US) 1999-10-19 US claimed
US-5700577-A Molecular grafting to energetically treated polyesters to promote adhesion of gelatin-containing layers EASTMAN KODAK COMPANY (US) 1997-12-23 US claimed
EP-0785466-A1 Molecular grafting of hardener/gelatin blends to energetically treated polyesters to promote adhesion of layers EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1997-07-23 EP claimed
EP-0736801-A2 Molecular grafting to energetically treated polyesters to promote adhesion of gelatin-containing layers EASTMAN KODAK COMPANY (US) 1996-10-09 EP claimed
US-5563029-A COATING TREATED SURFACE WITH A DILUTE AMINE REACTIVE HARDENER SOLUTION; DRYING; APPLYING PHOTOGRAPHIC EMULSION EASTMAN KODAK COMPANY (US) 1996-10-08 US claimed
US-4568635-A TETRASUBSTITUTED THIOUREA AS SOLVENT AND VINYL-SULFONYL CONTAING COMPOUND AS HARDENER FUJI PHOTO FILM CO., LTD. (JP) 1986-02-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130272991-A1 ION BINDING POLYMERS AND USES THEREOF ATP6V1B1, KCNN3, SLC9A3 TSHR 3454/4885SMN1; SMN2 4527/4885MAPT 3379/4885
US-20140286891-A1 ION BINDING POLYMERS AND USES THEREOF ATP6V1B1, KCNN3, SLC9A3 TSHR 3454/4885SMN1; SMN2 4527/4885MAPT 3379/4885
US-11197887-B2 Proton-binding polymers for oral administration SLC9A1, HRH2, SLC9A2 TSHR 1639/4885SMN1; SMN2 1911/4885MAPT 3207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.