SCHEMBL2593469

SCHEMBL2593469

O=C(O)CCCC(=O)ON1C(=O)CCC1=O.OCC(CO)(CO)CO

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
SLC22A6 Q4U2R8 1/20 0.33
PSMB8 P28062 1/20 0.33
PSMB5 P28074 1/20 0.33
CYP1A2 P05177 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CAMK2A Q9UQM7 1/20 0.31
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2589620 0.91 PSMB8 (0.34) PSMB8PSMB5
SCHEMBL34382 0.91 TSHR (0.44) TSHRSLC22A6PSMB8PSMB5CYP1A2
Ethylene Glycol SCHEMBL6129445 0.89 TSHR (0.40) TSHRSLC22A6PSMB8PSMB5CYP1A2
SCHEMBL290460 0.87 LMNA (0.41) TSHRSLC22A6SMN1; SMN2MEN1GAA
SCHEMBL25408775 0.85 TSHR (0.43) TSHRSLC22A6SMN1; SMN2MEN1GAA
SCHEMBL25408300 0.85 TSHR (0.43) TSHRSLC22A6SMN1; SMN2MEN1GAA
SCHEMBL25407766 0.85 TSHR (0.43) TSHRSLC22A6SMN1; SMN2MEN1GAA
SCHEMBL905403 0.85 TSHR (0.43) TSHRSLC22A6SMN1; SMN2MEN1GAA
SCHEMBL336648 0.85 TSHR (0.43) TSHRSLC22A6SMN1; SMN2MEN1GAA
SCHEMBL1230060 0.85 TSHR (0.43) TSHRSLC22A6SMN1; SMN2MEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190263750-A1 IN VIVO GELLING PHARMACEUTICAL PRE-FORMULATION THERAGENICS CORPORATION 2019-08-29 US claimed
US-10189773-B2 In-vivo gelling pharmaceutical pre-formulation MEDICUS BIOSCIENCES, LLC (US) 2019-01-29 US claimed
EP-2846847-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT Medicus Biosciences LLC (US) 2015-03-18 EP claimed
WO-2013170195-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT MEDICUS BIOSCIENCES, LLC (US) 2013-11-14 WO claimed
US-20130116341-A1 IN-VIVO GELLING PHARMACEUTICAL PRE-FORMULATION MEDICUS BIOSCIENCES, LLC (US) 2013-05-09 US claimed
WO-2011140519-A2 IN VIVO GELLING PHARMACEUTICAL PRE-FORMULATION MEDICUS BIOSCIENCES, LLC (US) 2011-11-10 WO claimed
US-20230218799-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT AQUARIAN CREDIT FUNDING LLC 2023-07-13 US disclosed
EP-2968680-B1 SOLID POLYGLYCOL-BASED BIOCOMPATIBLE PRE-FORMULATION C P MEDICAL CORP (US) 2023-05-03 EP disclosed
US-11596710-B2 Biocompatible hydrogel treatments for retinal detachment AQUARIAN CREDIT FUNDING LLC 2023-03-07 US disclosed
US-20210322785-A1 COMPOSITIONS AND METHODS FOR TREATING WOUNDS THERAGENICS CORPORATION 2021-10-21 US disclosed
EP-3893785-A1 COMPOSITIONS AND METHODS FOR TREATING WOUNDS C.P. Medical Corporation (US) 2021-10-20 EP disclosed
US-11083821-B2 Biocompatible hydrogel polymer formulations for the controlled delivery of biomolecules C.P. MEDICAL CORPORATION (US) 2021-08-10 US disclosed
US-20200316249-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT AQUARIAN CREDIT FUNDING LLC 2020-10-08 US disclosed
WO-2014153004-A1 SOLID POLYGLYCOL-BASED BIOCOMPATIBLE PRE-FORMULATION MEDICUS BIOSCIENCES LLC (US) 2014-09-25 WO disclosed
US-20140271528-A1 SOLID POLYGLYCOL-BASED BIOCOMPATIBLE PRE-FORMULATION MEDICUS BIOSCIENCES LLC (US) 2014-09-18 US disclosed
US-20140248231-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT MEDICUS BIOSCIENCES LLC (US) 2014-09-04 US disclosed
EP-2708224-A1 Biocompatible hydrogel polymer formulations for the controlled delivery of biomolecules Medicus Biosciences LLC (US) 2014-03-19 EP disclosed
WO-2013170195-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT MEDICUS BIOSCIENCES, LLC (US) 2013-11-14 WO disclosed
US-20130116341-A1 IN-VIVO GELLING PHARMACEUTICAL PRE-FORMULATION MEDICUS BIOSCIENCES, LLC (US) 2013-05-09 US disclosed
WO-2011140519-A2 IN VIVO GELLING PHARMACEUTICAL PRE-FORMULATION MEDICUS BIOSCIENCES, LLC (US) 2011-11-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10189773-B2 In-vivo gelling pharmaceutical pre-formulation FURIN, ARFGAP1, MGST1 TSHR 4254/4885SLC22A6 2899/4885PSMB8 1695/4885
US-20230218799-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT ALDH1A2, RB1, UACA TSHR 1883/4885SLC22A6 4502/4885PSMB8 2250/4885
US-11083821-B2 Biocompatible hydrogel polymer formulations for the controlled delivery of biomolecules HMGB1, HDGF, CRYAA TSHR 2909/4885SLC22A6 1675/4885PSMB8 1033/4885
US-11596710-B2 Biocompatible hydrogel treatments for retinal detachment ALDH1A2, RB1, UACA TSHR 1883/4885SLC22A6 4502/4885PSMB8 2250/4885
US-20190263750-A1 IN VIVO GELLING PHARMACEUTICAL PRE-FORMULATION FURIN, ARFGAP1, MGST1 TSHR 4398/4885SLC22A6 3009/4885PSMB8 1715/4885
US-20130116341-A1 IN-VIVO GELLING PHARMACEUTICAL PRE-FORMULATION FURIN, ARFGAP1, MGST1 TSHR 4254/4885SLC22A6 2899/4885PSMB8 1695/4885
US-20200316249-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT ALDH1A2, RB1, UACA TSHR 1883/4885SLC22A6 4502/4885PSMB8 2250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.