Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2591287 | 0.77 | KDM4E (0.42) | MAPTSMN1; SMN2ALDH1A1CYP2C9KDM4E | |
| SCHEMBL2594821 | 0.75 | HCRTR2 (0.50) | MAPTSMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL7709349 | 0.74 | GAA (0.43) | PPARGMAPTSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL2586420 | 0.63 | HCRTR2 (0.54) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7554160 | 0.62 | CCR2 (0.57) | PPARGMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9517850 | 0.60 | PPARG (0.45) | PPARGPTGDR2MAPTSMN1; SMN2RAB9A | |
| SCHEMBL17437846 | 0.60 | HTR4 (0.56) | — | |
| SCHEMBL7050743 | 0.59 | POLB (0.51) | PPARGSMN1; SMN2ALDH1A1CYP2C9L3MBTL1 | |
| SCHEMBL1715 | 0.59 | LMNA (0.59) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL20769804 | 0.59 | LMNA (0.59) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011138266-A1 | INDOLIZINE AND IMIDAZOPYRIDINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | EVOTEC AG (DE) | 2011-11-10 | — | — | WO | disclosed |