Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.31 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3274358 | 0.83 | MEN1 (0.43) | CYP3A4USP2ALDH1A1MAPTKMT2A | |
| SCHEMBL13269603 | 0.82 | ALDH1A1 (0.33) | ALDH1A1LMNA | |
| SCHEMBL18077441 | 0.77 | HPGD (0.39) | CYP3A4USP2ALDH1A1MAPTKMT2A | |
| SCHEMBL1313257 | 0.77 | CYP3A4 (0.35) | CYP3A4USP2ALDH1A1MAPTKMT2A | |
| SCHEMBL6551606 | 0.76 | CYP3A4 (0.38) | CYP3A4USP2ALDH1A1MAPTKMT2A | |
| SCHEMBL1225993 | 0.74 | KMT2A (0.41) | CYP3A4USP2ALDH1A1MAPTNOS3 | |
| SCHEMBL1087300 | 0.74 | NOS3 (0.37) | ALDH1A1MAPTNOS3NOS1NOS2 | |
| SCHEMBL10383900 | 0.73 | ALDH1A1 (0.39) | CYP3A4ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL13051720 | 0.73 | CYP3A4 (0.40) | CYP3A4USP2ALDH1A1MAPTKMT2A | |
| SCHEMBL3268412 | 0.73 | CCNB2 (0.43) | USP2MAPTKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242471-A1 | THYROMIMETICS | AUTOBAHN THERAPEUTICS, INC. | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242471-A1 | THYROMIMETICS | TPO, THOP1, THRB | CYP3A4 2516/4885USP2 2584/4885ALDH1A1 1458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.