Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN4A | P35499 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25955573 | 0.83 | ITGB2 (0.33) | TRPV1PIK3CAKCNH2SCN9ASCN5A | |
| SCHEMBL25340424 | 0.78 | SCN9A (0.35) | PDE10ALTA4HPIK3CAKCNH2SCN9A | |
| SCHEMBL30543994 | 0.78 | SCN9A (0.35) | PDE10ALTA4HPIK3CAKCNH2SCN9A | |
| SCHEMBL25955647 | 0.76 | PDE10A (0.40) | PDE10A | |
| SCHEMBL25955585 | 0.74 | GPR142 (0.34) | TRPV1PIK3CAKCNH2SCN9ASCN5A | |
| SCHEMBL21780467 | 0.72 | KCNH2 (0.45) | TRPV1PIK3CAKCNH2SCN9ASCN1A | |
| SCHEMBL22563248 | 0.71 | TLR8 (0.36) | TRPV1PIK3CAKCNH2PIK3CBPIK3CG | |
| SCHEMBL21780488 | 0.68 | ROCK2 (0.36) | TRPV1PIK3CAKCNH2CYP2D6CYP2C9 | |
| SCHEMBL25431600 | 0.68 | PDE10A (0.43) | PDE10ATRPV1 | |
| SCHEMBL30544064 | 0.68 | PDE10A (0.43) | PDE10ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |