SCHEMBL25960673

SCHEMBL25960673

COc1ccccc1-c1ccccc1Oc1ccc(C(C)=O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.56
MAPT P10636 2/20 0.56
HPGD P15428 1/20 0.56
L3MBTL1 Q9Y468 3/20 0.52
ALDH1A1 P00352 2/20 0.52
MAPK1 P28482 1/20 0.52
HTT P42858 1/20 0.52
BACE1 P56817 1/20 0.51
KMT2A Q03164 3/20 0.49
TTR P02766 1/20 0.49
MEN1 O00255 2/20 0.48
BRD4 O60885 1/20 0.46
NPSR1 Q6W5P4 1/20 0.45
NPC1 O15118 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MAOB P27338 2/20 0.44
PDE10A Q9Y233 1/20 0.44
LPAR1 Q92633 1/20 0.43
LPAR5 Q9H1C0 1/20 0.43
LMNA P02545 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9861909 0.93 MAPT (0.64) RAB9AMAPTHPGDL3MBTL1ALDH1A1
SCHEMBL1682171 0.88 HTT (0.68) RAB9AMAPTHPGDL3MBTL1ALDH1A1
SCHEMBL17879940 0.83 MAPT (0.49) RAB9AMAPTL3MBTL1ALDH1A1MAPK1
SCHEMBL12189290 0.81 L3MBTL1 (0.60) MAPTL3MBTL1ALDH1A1BACE1SMN1; SMN2
SCHEMBL25908089 0.81 PTGS2 (0.59) RAB9AMAPTHPGDTTRBRD4
SCHEMBL25908092 0.80 MAPT (0.51) RAB9AMAPTHPGDBACE1SMN1; SMN2
SCHEMBL16694449 0.79 S100A4 (0.65) MAPTL3MBTL1ALDH1A1KMT2AMEN1
SCHEMBL10588626 0.78 MAPT (0.62) RAB9AMAPTHPGDL3MBTL1ALDH1A1
SCHEMBL4743129 0.78 MAPT (0.62) RAB9AMAPTHPGDL3MBTL1ALDH1A1
SCHEMBL5608673 0.78 HPGD (0.62) RAB9AMAPTHPGDL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230245796-A1 Insulated conductor for use in a winding, winding derived therefrom and corresponding manufacturing methods ARKEMA FRANCE (FR) 2023-08-03 US disclosed