SCHEMBL25973992

SCHEMBL25973992

O=C(c1ccccc1)c1ccc2c(c1)C=CC(c1ccccc1)(c1ccc(N3CCOCC3)cc1)O2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 6/20 0.47
NPC1 O15118 5/20 0.47
HPGD P15428 5/20 0.47
TSHR P16473 4/20 0.47
RAB9A P51151 4/20 0.47
TP53 P04637 3/20 0.47
ALOX15 P16050 2/20 0.47
PIK3CD O00329 1/20 0.47
PIK3CA P42336 1/20 0.47
PIK3CB P42338 1/20 0.47
PIK3CG P48736 1/20 0.47
PRKDC P78527 1/20 0.47
MAPK1 P28482 1/20 0.47
ALDH1A1 P00352 9/20 0.44
MAPT P10636 6/20 0.44
HSD17B10 Q99714 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
LMNA P02545 1/20 0.44
STAT1 P42224 1/20 0.44
NPSR1 Q6W5P4 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25968633 0.78 CES2 (0.43) NPC1HPGDRAB9AMAPK1ALDH1A1
SCHEMBL50238 0.76 SMN1; SMN2 (0.74) SMN1; SMN2NPC1HPGDTSHRRAB9A
SCHEMBL25106659 0.72 NPC1 (0.46) SMN1; SMN2NPC1HPGDTSHRRAB9A
SCHEMBL7479031 0.71 SMN1; SMN2 (0.43) SMN1; SMN2NPC1HPGDTSHRRAB9A
SCHEMBL14982101 0.71 NPC1 (0.76) SMN1; SMN2NPC1HPGDTSHRRAB9A
SCHEMBL29375632 0.70 KDM4E (0.40) SMN1; SMN2NPC1HPGDTSHRRAB9A
SCHEMBL1408640 0.70 KDM4E (0.40) SMN1; SMN2NPC1HPGDTSHRRAB9A
SCHEMBL482234 0.70 COXFA4 (0.49) SMN1; SMN2NPC1HPGDRAB9ATP53
SCHEMBL2742813 0.70 NPC1 (0.66) SMN1; SMN2NPC1HPGDTSHRRAB9A
SCHEMBL4670962 0.69 PRKDC (0.39) SMN1; SMN2NPC1HPGDTSHRRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240066790-A1 Process and apparatus for locally polymerizing a starting material by dual color photopolymerization and method for volumetric printing of a shaped body XOLO GMBH (DE) 2024-02-29 US disclosed
US-20240066790-A1 Process and apparatus for locally polymerizing a starting material by dual color photopolymerization and method for volumetric printing of a shaped body XOLO GMBH (DE) 2024-02-29 US disclosed
EP-4282655-A2 PROCESS AND APPARATUS FOR LOCALLY POLYMERIZING A STARTING MATERIAL BY DUAL COLOR PHOTOPOLYMERIZATION AND METHOD FOR VOLUMETRIC PRINTING OF A SHAPED BODY xolo GmbH (DE) 2023-11-29 EP disclosed
EP-4224253-B1 PROCESS, APPARATUS AND PHOTOSWITCHABLE PHOTOINITIATORS FOR LOCALLY POLYMERIZING A STARTING MATERIAL BY DUAL COLOR PHOTOPOLYMERIZATION AND METHOD FOR VOLUMETRIC PRINTING OF A SHAPED BODY XOLO GMBH (DE) 2023-11-15 EP disclosed
EP-4224253-A2 PROCESS, APPARATUS AND PHOTOSWITCHABLE PHOTOINITIATORS FOR LOCALLY POLYMERIZING A STARTING MATERIAL BY DUAL COLOR PHOTOPOLYMERIZATION AND METHOD FOR VOLUMETRIC PRINTING OF A SHAPED BODY Xolo GmbH (DE) 2023-08-09 EP disclosed