SCHEMBL25968868

SCHEMBL25968868

Cc1cc(F)c(N2CCC(COc3ccc(Cl)c(N)c3C)CC2)c(F)c1

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 10/20 0.41
DCPS Q96C86 5/20 0.39
SCD O00767 1/20 0.35
MGLL Q99685 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20612937 0.89 FFAR4 (0.42) FFAR4DCPS
SCHEMBL25968983 0.81 FFAR4 (0.43) FFAR4MGLL
SCHEMBL25968959 0.77 FFAR4 (0.37) FFAR4DCPSMGLL
SCHEMBL20613003 0.75 FFAR4 (0.43) FFAR4
SCHEMBL20613072 0.74 SLC6A9 (0.41) FFAR4DCPSSCD
SCHEMBL25969105 0.74 MGLL (0.44) FFAR4MGLL
SCHEMBL20612907 0.73 FFAR4 (0.41) FFAR4DCPS
SCHEMBL25969082 0.73 FFAR4 (0.37) FFAR4DCPS
SCHEMBL20612909 0.72 FFAR4 (0.44) FFAR4DCPSMGLL
SCHEMBL25968473 0.72 FFAR4 (0.47) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3421454-B9 PIPERIDINE DERIVATIVE OTSUKA PHARMA CO LTD (JP) 2023-08-09 EP disclosed