Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.46 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.40 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25970571 | 0.82 | UCHL1 (0.47) | KDM1AHSD11B1UCHL1OPRD1NPC1 | |
| SCHEMBL22725293 | 0.77 | HSD17B10 (0.48) | HSD11B1UCHL1NPC1MEN1KMT2A | |
| SCHEMBL28521198 | 0.77 | HSD17B10 (0.48) | HSD11B1UCHL1NPC1MEN1KMT2A | |
| SCHEMBL22725305 | 0.77 | HSD17B10 (0.48) | HSD11B1UCHL1NPC1MEN1KMT2A | |
| SCHEMBL25970105 | 0.76 | HSD17B10 (0.50) | HSD11B1UCHL1NPC1MEN1KMT2A | |
| SCHEMBL25970081 | 0.76 | HSD17B10 (0.50) | HSD11B1UCHL1NPC1MEN1KMT2A | |
| SCHEMBL25970131 | 0.74 | HSD17B10 (0.49) | HSD11B1UCHL1NPC1MEN1KMT2A | |
| SCHEMBL2109651 | 0.72 | RBP4 (0.51) | KDM1AHSD11B1 | |
| SCHEMBL29087405 | 0.72 | HSD17B10 (0.46) | HSD11B1UCHL1NPC1MEN1KMT2A | |
| SCHEMBL25970274 | 0.72 | HSD17B10 (0.46) | KDM1AHSD11B1NPC1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718638-B2 | Compounds, compositions and methods for synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2023-08-08 | — | — | US | disclosed |
| US-11718638-B2 | Compounds, compositions and methods for synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2023-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718638-B2 | Compounds, compositions and methods for synthesis | ALKBH1, DUT, RNGTT | KDM1A 3124/4885HSD11B1 4388/4885UCHL1 506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.