Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 9/20 | 0.41 |
| ▸ | FPR2 | P25090 | 2/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25341793 | 1.00 | TRPV1 (0.47) | TRPV1KIF11SCN9AFPR2CHEK2 | |
| SCHEMBL25340735 | 0.85 | MKNK1 (0.42) | KIF11SCN9AFPR2CHEK2CASP1 | |
| SCHEMBL30519468 | 0.83 | SCN9A (0.41) | KIF11SCN9AFPR2CHEK2MKNK1 | |
| SCHEMBL25340768 | 0.83 | SCN9A (0.41) | KIF11SCN9AFPR2CHEK2MKNK1 | |
| SCHEMBL25340543 | 0.80 | SCN9A (0.41) | SCN9AFPR2CHEK2MKNK1MKNK2 | |
| SCHEMBL30519343 | 0.80 | SCN9A (0.41) | SCN9AFPR2CHEK2MKNK1MKNK2 | |
| SCHEMBL25973972 | 0.80 | TRPV1 (0.39) | TRPV1RAB9A | |
| SCHEMBL25973973 | 0.79 | THRB (0.41) | TRPV1SCN9ARAB9ASMN1; SMN2 | |
| SCHEMBL25974745 | 0.78 | KIF11 (0.51) | KIF11RAB9ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL30519279 | 0.76 | LMNA (0.39) | TRPV1KIF11SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146513-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |