Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1B | O00238 | 1/20 | 0.30 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.30 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633749 | 0.75 | MPO (0.41) | BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL21098659 | 0.75 | KMT2A (0.36) | — | |
| SCHEMBL25975016 | 0.74 | OPRM1 (0.34) | — | |
| SCHEMBL634040 | 0.68 | ALDH1A1 (0.34) | — | |
| Selectan SCHEMBL117423 | 0.68 | — | — | |
| SCHEMBL25767985 | 0.65 | DRD2 (0.35) | SLC6A4 | |
| SCHEMBL26031341 | 0.64 | OPRM1 (0.35) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24681533 | 0.63 | OPRM1 (0.51) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25975010 | 0.62 | CNR2 (0.40) | — | |
| SCHEMBL15119914 | 0.62 | HSD11B1 (0.40) | BMPR1BBMPR1AACVRL1ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |