Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL588936 | 0.82 | AOC3 (0.37) | — | |
| SCHEMBL26031341 | 0.81 | OPRM1 (0.35) | OPRM1 | |
| SCHEMBL25975003 | 0.74 | BMPR1B (0.30) | — | |
| SCHEMBL25767985 | 0.73 | DRD2 (0.35) | OPRM1 | |
| SCHEMBL27389451 | 0.69 | HTR6 (0.36) | — | |
| SCHEMBL117132 | 0.69 | — | — | |
| SCHEMBL25975010 | 0.68 | CNR2 (0.40) | — | |
| SCHEMBL17083420 | 0.63 | HSD11B1 (0.36) | CASP3 | |
| SCHEMBL256009 | 0.62 | MAP2K2 (0.41) | CASP3 | |
| SCHEMBL31434274 | 0.61 | MAPT (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |