Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 2/20 | 0.32 |
| ▸ | CDK8 | P49336 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 6/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26640900 | 0.82 | DRD2 (0.42) | CDK4CDK2CDK6DRD2LMNA | |
| SCHEMBL26032299 | 0.79 | POLB (0.41) | CDK4ADORA2AADORA1LMNAPOLB | |
| SCHEMBL25975830 | 0.78 | LMNA (0.40) | ADORA2AADORA1DRD2LMNAPOLB | |
| SCHEMBL25975832 | 0.78 | PDCD1 (0.42) | CDK4CDK2CDK6ADORA2AADORA1 | |
| SCHEMBL26639986 | 0.77 | ALDH1A1 (0.36) | CDK4CDK2CDK6DRD2LMNA | |
| SCHEMBL14853336 | 0.77 | HRH3 (0.37) | CDK4ADORA2AADORA1DRD2LMNA | |
| SCHEMBL16389169 | 0.76 | DRD2 (0.41) | DRD2POLBPRMT5CCNCCDK8 | |
| SCHEMBL26032153 | 0.76 | MEN1 (0.40) | DRD2POLBPRMT5CCNCCDK8 | |
| SCHEMBL14566140 | 0.75 | ADORA2A (0.40) | CDK4CDK2CDK6ADORA2AADORA1 | |
| SCHEMBL14566143 | 0.75 | CDK4 (0.41) | CDK4CDK2CDK6ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |