Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15888456 | 0.89 | MAPK1 (0.37) | MAPK1CA4ALDH1A1ALOX15ESR1 | |
| SCHEMBL704188 | 0.82 | MAPK1 (0.36) | MAPK1CA4ALDH1A1ALOX15ESR1 | |
| SCHEMBL79874 | 0.79 | MAPK1 (0.37) | MAPK1CA4ALDH1A1ALOX15ESR1 | |
| SCHEMBL4835281 | 0.76 | MAPK1 (0.34) | MAPK1ALDH1A1ALOX15ESR1ESR2 | |
| SCHEMBL31318429 | 0.76 | MAPK1 (0.34) | MAPK1ALDH1A1ALOX15ESR1ESR2 | |
| SCHEMBL18924906 | 0.76 | ALDH1A1 (0.41) | MAPK1ALDH1A1ALOX15ESR1ESR2 | |
| SCHEMBL19720997 | 0.76 | MAPK1 (0.34) | MAPK1ALDH1A1ALOX15ESR1ESR2 | |
| SCHEMBL707572 | 0.76 | MAPK1 (0.34) | MAPK1ALDH1A1ALOX15ESR1ESR2 | |
| SCHEMBL707090 | 0.76 | MAPK1 (0.34) | MAPK1ALDH1A1ALOX15ESR1ESR2 | |
| SCHEMBL26964680 | 0.76 | MAPK1 (0.34) | MAPK1ALDH1A1ALOX15ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4227308-A1 | TETRAHYDROBENZOFURODIAZEPINONE COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | Japan Tobacco Inc. (JP) | 2023-08-16 | — | — | EP | disclosed |