Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8465571 | 0.86 | KMT2A (0.59) | CYP1A2CYP3A4CYP2C9CYP2C19THRB | |
| SCHEMBL9710367 | 0.84 | KMT2A (0.62) | KMT2AMEN1RAB9ANPC1LMNA | |
| SCHEMBL9780958 | 0.79 | KMT2A (0.67) | THRBKMT2AMEN1LMNAPLAU | |
| SCHEMBL3342586 | 0.74 | L3MBTL1 (0.80) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL19501795 | 0.74 | CYP1A2 (0.88) | CYP1A2CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL3469024 | 0.74 | CYP3A4 (0.67) | CYP1A2CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL9780586 | 0.74 | KMT2A (0.65) | CYP3A4KMT2AMEN1RAB9AL3MBTL1 | |
| SCHEMBL10631666 | 0.74 | KMT2A (0.64) | CYP1A2CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL5902886 | 0.73 | MAPT (0.62) | CYP1A2CYP3A4RAB9ATP53MAPT | |
| SCHEMBL11085038 | 0.72 | MEN1 (0.54) | CYP1A2CYP3A4CYP2C9CYP2C19THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234911-A1 | METHOD FOR SYNTHESIZING DICLOFENAC SODIUM | FUDAN UNIVERSITY (CN) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234911-A1 | METHOD FOR SYNTHESIZING DICLOFENAC SODIUM | SULT2A1, CRYAA, AADAC | CYP1A2 37/4885CYP3A4 92/4885CYP2C9 31/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.