Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20150803 | 0.82 | HPGD (0.37) | MAPTTSHRHTTHSD17B10 | |
| SCHEMBL20148179 | 0.82 | HPGD (0.37) | MAPTTSHRHTTHSD17B10 | |
| SCHEMBL6438818 | 0.74 | ALDH1A1 (0.43) | TSHR | |
| SCHEMBL21649876 | 0.70 | TRPA1 (0.39) | MAPTTSHRHTTHSD17B10 | |
| SCHEMBL31633781 | 0.69 | ACHE (0.36) | TSHR | |
| SCHEMBL144695 | 0.69 | ACHE (0.36) | TSHR | |
| SCHEMBL24749936 | 0.68 | NFE2L2 (0.39) | MAPT | |
| SCHEMBL22484321 | 0.68 | EIF4A3 (0.31) | — | |
| SCHEMBL21297955 | 0.68 | — | — | |
| SCHEMBL21667992 | 0.67 | NFE2L2 (0.38) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250074-A1 | PROCESS FOR SYNTHESIS OF QUINAZOLINE COMPOUNDS | GENENTECH, INC. (US) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250074-A1 | PROCESS FOR SYNTHESIS OF QUINAZOLINE COMPOUNDS | HCCS, NQO2, SQLE | MAPT 3788/4885TSHR 3734/4885HTT 4101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.