⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15023800 | 0.78 | — | — | |
| SCHEMBL15023802 | 0.78 | — | — | |
| SCHEMBL790072 | 0.74 | TP53 (0.32) | — | |
| SCHEMBL2598542 | 0.73 | LMNA (0.43) | — | |
| SCHEMBL5067770 | 0.68 | DPP4 (0.35) | — | |
| SCHEMBL5222630 | 0.67 | S1PR3 (0.40) | — | |
| SCHEMBL6274182 | 0.67 | GNAI3 (0.41) | — | |
| SCHEMBL21409408 | 0.66 | POLB (0.35) | — | |
| SCHEMBL3877432 | 0.66 | DPP4 (0.37) | — | |
| SCHEMBL28037367 | 0.66 | POLB (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571864-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | Array Biopharma, Inc. (US) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011146335-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | ARRAY BIOPHARMA INC. (US) | 2011-11-24 | — | — | WO | disclosed |