Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | TLR4 | O00206 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20815439 | 0.82 | KCNH2 (0.32) | POLBHPGDDPP4TACR1KCNH2 | |
| SCHEMBL5067770 | 0.81 | DPP4 (0.35) | POLBHPGDDPP4S1PR5PKM | |
| SCHEMBL6274182 | 0.80 | GNAI3 (0.41) | POLBHPGDDPP4TACR1S1PR5 | |
| SCHEMBL23071604 | 0.80 | TACR1 (0.35) | POLBHPGDTACR1MEN1KMT2A | |
| SCHEMBL21409408 | 0.79 | POLB (0.35) | POLBHPGDDPP4PKMALOX5 | |
| SCHEMBL3877432 | 0.79 | DPP4 (0.37) | POLBHPGDDPP4PKMALOX5 | |
| SCHEMBL5500987 | 0.78 | DPP4 (0.33) | POLBHPGDDPP4ALOX5MAPT | |
| SCHEMBL5222630 | 0.77 | S1PR3 (0.40) | DPP4S1PR5PKMALOX5S1PR1 | |
| SCHEMBL28040142 | 0.77 | THRB (0.35) | POLBHPGDDPP4TACR1PKM | |
| SCHEMBL7733041 | 0.76 | L3MBTL1 (0.43) | POLBDPP4S1PR5S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105153119-A | Pyridylpyrimidyl amine compounds or pyridylpyridyl amine compounds and application thereof | GUANGZHOU KEQIN NEW MEDICINE DESIGN CO LTD | 2015-12-16 | — | — | CN | disclosed |