Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17278421 | 0.86 | L3MBTL1 (0.36) | L3MBTL1GAACHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL14431307 | 0.77 | GAA (0.41) | L3MBTL1GAACHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL23626191 | 0.77 | SMN1; SMN2 (0.34) | L3MBTL1GAACHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL30952890 | 0.77 | SMN1; SMN2 (0.34) | L3MBTL1GAACHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL24910475 | 0.77 | L3MBTL1 (0.43) | L3MBTL1GAACHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL25097257 | 0.77 | TERT (0.50) | L3MBTL1GAACHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL12228828 | 0.76 | RAB9A (0.51) | L3MBTL1GAASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL24403092 | 0.75 | RAB9A (0.50) | SMN1; SMN2POLBALDH1A1RAB9ANPC1 | |
| SCHEMBL10785167 | 0.75 | SMN1; SMN2 (0.47) | L3MBTL1GAACHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL8221475 | 0.74 | L3MBTL1 (0.41) | L3MBTL1GAACHRNB2CHRNA4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11701331-B2 | Toxic aldehyde related diseases and treatment | ALDEYRA THERAPEUTICS, INC. (US) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11701331-B2 | Toxic aldehyde related diseases and treatment | ALDH1A2, ALDH2, ALDH1A1 | L3MBTL1 286/4885GAA 435/4885CHRNB2 3378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.