SCHEMBL2600795

SCHEMBL2600795

CC(OCCCCCC(=O)OCC(=O)O)C(=O)OCC(=O)O

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PAM P19021 2/20 0.57
DGKA P23743 1/20 0.41
MAPT P10636 1/20 0.39
LMNA P02545 3/20 0.38
ALDH1A1 P00352 2/20 0.38
PRSS1 P07477 1/20 0.37
PRSS2 P07478 1/20 0.37
PRSS3 P35030 1/20 0.37
PRKCA P17252 1/20 0.36
PRKCE Q02156 1/20 0.36
PRKCQ Q04759 1/20 0.36
PRKCD Q05655 1/20 0.36
DNM1 Q05193 1/20 0.35
KDM4E B2RXH2 1/20 0.34
DUSP3 P51452 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12287044 0.94 PAM (0.51) PAMDGKAMAPTLMNAALDH1A1
SCHEMBL15445477 0.79 PAM (0.59) PAMDGKAMAPTLMNAALDH1A1
SCHEMBL27714306 0.78 PAM (0.79) PAMDGKAMAPTLMNAALDH1A1
SCHEMBL27697262 0.78 PAM (0.79) PAMDGKAMAPTLMNAALDH1A1
SCHEMBL1845790 0.78 PAM (0.79) PAMDGKAMAPTLMNAALDH1A1
SCHEMBL2600796 0.77 PAM (0.41) PAM
SCHEMBL1845834 0.76 PAM (0.75) PAMDGKAMAPTLMNAALDH1A1
SCHEMBL5163437 0.76 PAM (0.65) PAMDGKAMAPTLMNAALDH1A1
SCHEMBL2738358 0.75 PAM (0.58) PAMDGKAMAPTLMNAALDH1A1
SCHEMBL9277620 0.75 PAM (0.86) PAMDGKAALDH1A1PRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130035402-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF BEZWADA BIOMEDICAL, LLC (US) 2013-02-07 US disclosed
US-20130035402-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF BEZWADA BIOMEDICAL, LLC (US) 2013-02-07 US disclosed
US-8309132-B2 Bioabsorbable polyesteramides and uses thereof BEZWADA BIOMEDICAL, LLC (US) 2012-11-13 US disclosed
US-8309132-B2 Bioabsorbable polyesteramides and uses thereof BEZWADA BIOMEDICAL, LLC (US) 2012-11-13 US disclosed
US-8163806-B2 Controlled release of biologically active compounds from multi-armed oligomers BEZWADA BIOMEDICAL, LLC (US) 2012-04-24 US disclosed
US-8163806-B2 Controlled release of biologically active compounds from multi-armed oligomers BEZWADA BIOMEDICAL, LLC (US) 2012-04-24 US disclosed
US-20120010284-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS FROM MULTI-ARMED OLIGOMERS BEZWADA BIOMEDICAL, LLC (US) 2012-01-12 US disclosed
US-20120010284-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS FROM MULTI-ARMED OLIGOMERS BEZWADA BIOMEDICAL, LLC (US) 2012-01-12 US disclosed
US-8026285-B2 Control release of biologically active compounds from multi-armed oligomers BEZWADA BIOMEDICAL, LLC (US) 2011-09-27 US disclosed
US-8026285-B2 Control release of biologically active compounds from multi-armed oligomers BEZWADA BIOMEDICAL, LLC (US) 2011-09-27 US disclosed
US-20090285896-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF BEZWADA BIOMEDICAL, LLC (US) 2009-11-19 US disclosed
US-20090285896-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF BEZWADA BIOMEDICAL, LLC (US) 2009-11-19 US disclosed
US-20090076174-A1 CONTROL RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS FROM MULTI-ARMED OLIGOMERS BEZWADA BIOMEDICAL, LLC (US) 2009-03-19 US disclosed
US-20090076174-A1 CONTROL RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS FROM MULTI-ARMED OLIGOMERS BEZWADA BIOMEDICAL, LLC (US) 2009-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090076174-A1 CONTROL RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS FROM MULTI-ARMED OLIGOMERS MME, CTSA, ALG1 PAM 587/4885DGKA 3158/4885MAPT 869/4885
US-20090285896-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF PAICS, UROD, PUF60 PAM 22/4885DGKA 926/4885MAPT 1542/4885
US-20120010284-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS FROM MULTI-ARMED OLIGOMERS MME, AADAC, LGMN PAM 534/4885DGKA 3147/4885MAPT 927/4885
US-20130035402-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF PAICS, UROD, PUF60 PAM 22/4885DGKA 926/4885MAPT 1542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.