SCHEMBL2600864

SCHEMBL2600864

CN[C@H](CO)C(=O)NCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 3/20 0.58
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA3 P07451 1/20 0.56
CA4 P22748 1/20 0.56
CA6 P23280 1/20 0.56
CA5A P35218 1/20 0.56
CA7 P43166 1/20 0.56
CACNA1C Q13936 1/20 0.56
SCN9A Q15858 1/20 0.56
CA9 Q16790 1/20 0.56
CA13 Q8N1Q1 1/20 0.56
CA14 Q9ULX7 1/20 0.56
CA5B Q9Y2D0 1/20 0.56
KMT2A Q03164 3/20 0.54
MME P08473 1/20 0.50
ALDH1A1 P00352 3/20 0.49
MEN1 O00255 2/20 0.49
SLC1A2 P43004 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20804412 0.87 POLB (0.57) MMP8CA12CA1CA2CA3
SCHEMBL14947756 0.87 POLB (0.57) MMP8CA12CA1CA2CA3
SCHEMBL8769547 0.85 MMP8 (0.59) MMP8CA12CA1CA2CA3
SCHEMBL8205298 0.84 CA12 (0.74) MMP8CA12CA1CA2CA3
SCHEMBL47275 0.84 CA12 (0.74) MMP8CA12CA1CA2CA3
SCHEMBL2600863 0.84 CA12 (0.74) MMP8CA12CA1CA2CA3
SCHEMBL1697369 0.84 CA12 (0.74) MMP8CA12CA1CA2CA3
SCHEMBL18435455 0.84 MMP8 (0.55) MMP8CA12CA1CA2CA3
SCHEMBL12505312 0.83 MMP8 (0.61) MMP8CA12CA1CA2CA3
SCHEMBL20720018 0.83 MMP8 (0.61) MMP8CA12CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120095251-A1 Process for Producing Lacosamide EUTICALS GMBH (DE) 2012-04-19 US disclosed
US-20110319649-A1 Intermediate for producing lacosamide and a process for its preparation and conversion to lacosamide EUTICALS GMBH (DE) 2011-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110319649-A1 Intermediate for producing lacosamide and a process for its preparation and conversion to lacosamide NAAA, MEP1B, BCHE MMP8 1953/4885CA12 138/4885CA1 11/4885
US-20120095251-A1 Process for Producing Lacosamide NAAA, TET3, GNMT MMP8 2694/4885CA12 168/4885CA1 126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.