Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 11/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSH | P09668 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.37 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.37 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.37 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.37 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.37 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.37 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.37 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.37 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.37 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22387819 | 0.91 | CTSS (0.40) | CTSSCTSBCTSKCTSLCTSH | |
| SCHEMBL30069324 | 0.88 | NTSR2 (0.37) | CTSSCTSBCTSKCTSLAPLNR | |
| SCHEMBL2623712 | 0.87 | APLNR (0.40) | CTSSCTSBCTSKCTSLCTSH | |
| SCHEMBL15745525 | 0.82 | APLNR (0.36) | CTSSCTSKCTSLCTSHAPLNR | |
| SCHEMBL15744687 | 0.81 | APLNR (0.40) | CTSSAPLNRPSMB11PSMA7PSMB1 | |
| SCHEMBL29380915 | 0.81 | OPRK1 (0.41) | OPRK1NTSR2NTSR1 | |
| SCHEMBL30069323 | 0.81 | OPRK1 (0.41) | OPRK1NTSR2NTSR1 | |
| SCHEMBL15745544 | 0.80 | CRHR1 (0.37) | APLNR | |
| SCHEMBL29398799 | 0.80 | CCNA2 (0.44) | OPRK1NTSR2NTSR1 | |
| SCHEMBL15744682 | 0.79 | MMP3 (0.40) | CTSSCTSBCTSKCTSLCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630742-B1 | CHEMILUMINESCENT PROBES FOR IMAGING/DETECTION OF PROTEASES | UNIV RAMOT (IL) | 2023-08-16 | — | — | EP | disclosed |