Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR2 | O95665 | 3/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.37 |
| ▸ | APLNR | P35414 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.36 |
| ▸ | NMT2 | O60551 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26019657 | 0.88 | CTSS (0.40) | NTSR2NTSR1APLNRCTSLCTSB | |
| SCHEMBL22387819 | 0.85 | CTSS (0.40) | CTSLCTSBCTSSCTSKOPRK1 | |
| SCHEMBL29380915 | 0.84 | OPRK1 (0.41) | NTSR2NTSR1OPRK1NMT2NMT1 | |
| SCHEMBL30069323 | 0.84 | OPRK1 (0.41) | NTSR2NTSR1OPRK1NMT2NMT1 | |
| SCHEMBL30906004 | 0.81 | ERAP2 (0.44) | NTSR2NTSR1OPRK1SLC15A2 | |
| SCHEMBL29531670 | 0.81 | OPRK1 (0.44) | NTSR2NTSR1OPRK1SLC15A2 | |
| SCHEMBL2623712 | 0.81 | APLNR (0.40) | APLNRCTSLCTSBCTSSCTSK | |
| SCHEMBL30645280 | 0.80 | OPRK1 (0.46) | NTSR2NTSR1OPRK1SLC15A2 | |
| SCHEMBL30692338 | 0.79 | NPY1R (0.41) | APLNROPRK1NMT2NMT1 | |
| SCHEMBL30645273 | 0.78 | NPY4R (0.47) | NTSR2NTSR1OPRK1SLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12173350-B2 | Chemiluminescent probes for imaging/detection of proteases | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2024-12-24 | — | — | US | disclosed |
| EP-3630742-B1 | CHEMILUMINESCENT PROBES FOR IMAGING/DETECTION OF PROTEASES | UNIV RAMOT (IL) | 2023-08-16 | — | — | EP | disclosed |
| CN-110944985-B | Chemiluminescent probe for imaging/detection of proteases | 特拉维夫大学拉玛特有限公司 | 2022-12-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12173350-B2 | Chemiluminescent probes for imaging/detection of proteases | ADAM12, ADAM17, PRCP | NTSR2 3569/4885NTSR1 2968/4885APLNR 1487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.