Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4103229 | 0.98 | EPHX2 (0.50) | TSHREPHX2LMNAALOX15ALDH1A1 | |
| SCHEMBL4103840 | 0.94 | TSHR (0.54) | TSHREPHX2LMNAALOX15ALDH1A1 | |
| SCHEMBL4103385 | 0.86 | TSHR (0.50) | TSHREPHX2LMNAALOX15ALDH1A1 | |
| SCHEMBL349163 | 0.85 | ALOX15 (0.43) | TSHREPHX2LMNAALOX15ALDH1A1 | |
| SCHEMBL4099875 | 0.84 | CYP1A2 (0.52) | EPHX2ALDH1A1SMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL2033309 | 0.82 | TSHR (0.54) | TSHREPHX2LMNAALDH1A1RECQL | |
| SCHEMBL4100220 | 0.82 | EPHX2 (0.51) | TSHREPHX2ALOX15ALDH1A1SMN1; SMN2 | |
| SCHEMBL4094098 | 0.82 | ADRA1A (0.49) | TSHREPHX2SMN1; SMN2RECQL | |
| SCHEMBL437938 | 0.81 | SMN1; SMN2 (0.50) | ALOX15ALDH1A1SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL4111544 | 0.81 | LMNA (0.54) | EPHX2LMNAALOX15ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912650-B2 | Bakuchiol derivatives, pharmaceutically acceptable salts thereof, and preparation method and use of the same | JIANGXI SHIMEI PHARMACEUTICAL CO., LTD (CN) | 2024-02-27 | — | — | US | disclosed |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | MALLE GERARD | 2009-08-06 | — | — | US | disclosed |
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | L'OREAL S.A. | 2009-06-04 | — | — | US | disclosed |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | L'OREAL S.A. (FR) | 2005-06-23 | — | — | US | disclosed |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | L'OREAL | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | KRT18, INMT, INHA | TSHR 1694/4885EPHX2 3781/4885LMNA 117/4885 |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | KRT18, KIT, PRDM7 | TSHR 3766/4885EPHX2 2648/4885LMNA 132/4885 |
| US-11912650-B2 | Bakuchiol derivatives, pharmaceutically acceptable salts thereof, and preparation method and use of the same | CEL, NPC1L1, LIPA | TSHR 2886/4885EPHX2 2026/4885LMNA 2781/4885 |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | KRT18, INHA, H1-5 | TSHR 3770/4885EPHX2 2936/4885LMNA 85/4885 |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | BHMT, KRT18, INMT | TSHR 1691/4885EPHX2 3448/4885LMNA 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.