SCHEMBL26035671

SCHEMBL26035671

CCCCCCCCCCCCCCCC(=O)NCC(C)(C)COCC(C)(C)CNC(=O)CC[C@H](NC)C(=O)NCC(C)(C)COCC(C)(C)CNC(=O)CCC(C)(C)/C=C\C(C)(C)CC

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.35
CNR1 P21554 4/20 0.34
CNR2 P34972 4/20 0.34
FAAH O00519 2/20 0.34
NOD1 Q9Y239 1/20 0.34
LPAR3 Q9UBY5 2/20 0.33
TRPV1 Q8NER1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25840094 0.84 GLP1R (0.36) GLP1RFAAHNOD1LPAR3
SCHEMBL26036004 0.83 BIRC2 (0.39) GLP1RFAAHNOD1LPAR3
SCHEMBL26034893 0.78 GLP1R (0.34) GLP1RCNR1CNR2NOD1LPAR3
SCHEMBL27143004 0.73 GLP1R (0.43) GLP1RNOD1LPAR3
SCHEMBL27117452 0.73 GLP1R (0.42) GLP1RNOD1LPAR3
SCHEMBL26035192 0.72 GLP1R (0.40) GLP1RFAAHNOD1LPAR3
SCHEMBL25848473 0.72 NOD1 (0.40) FAAHNOD1
SCHEMBL26034080 0.70 FAAH (0.47) CNR1CNR2FAAH
SCHEMBL21096814 0.69 FAAH (0.46) CNR1CNR2FAAH
SCHEMBL24341855 0.67 FAAH (0.44) CNR1CNR2FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 GLP1R 1683/4885CNR1 4167/4885CNR2 4501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.