SCHEMBL2604829

SCHEMBL2604829

c1ccc(-c2nc3ccccc3n2-c2ccc(-c3c4ccccc4c(-c4cccc5ccccc45)c4ccccc34)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.56
ESR2 Q92731 2/20 0.56
GRIA1 P42261 1/20 0.49
CACNG8 Q8WXS5 1/20 0.49
CACNG2 Q9Y698 1/20 0.49
PTGS2 P35354 1/20 0.45
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
HSP90AA1 P07900 1/20 0.44
MAPT P10636 1/20 0.44
RECQL P46063 1/20 0.44
ALDH1A1 P00352 7/20 0.43
HPGD P15428 2/20 0.43
KDM4E B2RXH2 1/20 0.43
HDAC1 Q13547 2/20 0.43
HDAC8 Q9BY41 2/20 0.43
HDAC6 Q9UBN7 2/20 0.43
HTT P42858 2/20 0.40
MAPK1 P28482 1/20 0.40
FLT3 P36888 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14000030 0.99 ESR1 (0.55) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL10028918 0.96 ESR1 (0.51) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL2604842 0.95 ESR1 (0.56) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL14363290 0.94 ESR2 (0.49) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL14000362 0.93 ESR1 (0.49) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL25769034 0.93 ESR2 (0.52) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL25769033 0.93 ESR2 (0.48) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL20216285 0.92 ESR1 (0.49) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL25688373 0.92 ESR1 (0.49) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL18144292 0.92 ESR1 (0.47) ESR1ESR2GRIA1CACNG8CACNG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12022728-B2 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2024-06-25 US disclosed
US-11877509-B2 Organic light-emitting element LG CHEM, LTD. 2024-01-16 US disclosed
US-11877509-B2 Organic light-emitting element LG CHEM, LTD. 2024-01-16 US disclosed
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-09-28 US disclosed
US-20230217821-A1 Light Emitting Device and Light Emitting Display Device Including the Same LG DISPLAY CO., LTD. (KR) 2023-07-06 US disclosed
US-20230217821-A1 Light Emitting Device and Light Emitting Display Device Including the Same LG DISPLAY CO., LTD. (KR) 2023-07-06 US disclosed
EP-4207995-A1 LIGHT EMITTING DEVICE AND LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG Display Co., Ltd. (KR) 2023-07-05 EP disclosed
US-20230209998-A1 ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-29 US disclosed
US-11552251-B2 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-01-10 US disclosed
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 US disclosed
US-20140183500-A1 ORGANIC ELECTROLUMINESCENCE IDEMITSU KOSAN CO., LTD. (JP) 2014-07-03 US disclosed
US-20140183500-A1 ORGANIC ELECTROLUMINESCENCE IDEMITSU KOSAN CO., LTD. (JP) 2014-07-03 US disclosed
US-20140131681-A1 ORGANIC ELECTROLUMINESCENT DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-05-15 US disclosed
US-20140131681-A1 ORGANIC ELECTROLUMINESCENT DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-05-15 US disclosed
US-20120091438-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-04-19 US disclosed
US-20120091438-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-04-19 US disclosed
US-20120074395-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-03-29 US disclosed
US-20120074395-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-03-29 US disclosed
US-20080193796-A1 ORGANIC ELECTROLUMINESCENT DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2008-08-14 US disclosed
US-20080193796-A1 ORGANIC ELECTROLUMINESCENT DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2008-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, OR10J3, TMEM109 ESR1 124/4885ESR2 596/4885GRIA1 605/4885
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, TMEM109, SLC39A14 ESR1 13/4885ESR2 26/4885GRIA1 1052/4885
US-11552251-B2 Organic electroluminescent element and electronic device L1CAM, ESR1, LEF1 ESR1 2/4885ESR2 10/4885GRIA1 366/4885
US-20230217821-A1 Light Emitting Device and Light Emitting Display Device Including the Same DBH, PRPH, NBAS ESR1 213/4885ESR2 1051/4885GRIA1 2026/4885
US-11877509-B2 Organic light-emitting element CRY1, CRY2, NR2E3 ESR1 4/4885ESR2 33/4885GRIA1 1310/4885
US-12022728-B2 Organic electroluminescent element and electronic device L1CAM, ESR1, LEF1 ESR1 2/4885ESR2 10/4885GRIA1 366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.