SCHEMBL2605857

SCHEMBL2605857

CC(=O)Nc1ccc(-c2ccc(O)cc2)cc1

nearest known ligand 0.87

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.87
MEN1 O00255 5/20 0.87
MAPT P10636 4/20 0.87
ALDH1A1 P00352 4/20 0.87
CA12 O43570 1/20 0.87
BRD4 O60885 1/20 0.87
NR1I2 O75469 1/20 0.87
CA1 P00915 1/20 0.87
CA2 P00918 1/20 0.87
MB P02144 1/20 0.87
CYP1A1 P04798 1/20 0.87
CA3 P07451 1/20 0.87
CYP3A4 P08684 1/20 0.87
RARG P13631 1/20 0.87
TSHR P16473 1/20 0.87
ALOX5AP P20292 1/20 0.87
CA4 P22748 1/20 0.87
CA7 P43166 1/20 0.87
NR1I3 Q14994 1/20 0.87
CA9 Q16790 1/20 0.87

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetaminophen SCHEMBL8937727 0.93 KMT2A (1.00) KMT2AMEN1MAPTALDH1A1CA12
Acetaminophen SCHEMBL252939 0.93 KMT2A (1.00) KMT2AMEN1MAPTALDH1A1CA12
Acetaminophen SCHEMBL3480 0.93 KMT2A (1.00) KMT2AMEN1MAPTALDH1A1CA12
Acetaminophen SCHEMBL8197085 0.91 KMT2A (0.95) KMT2AMEN1MAPTALDH1A1CA12
Acetaminophen SCHEMBL10325382 0.91 KMT2A (0.95) KMT2AMEN1MAPTALDH1A1CA12
Acetaminophen SCHEMBL20541508 0.91 ALDH1A1 (0.95) KMT2AMEN1MAPTALDH1A1CA12
Acetaminophen SCHEMBL8959271 0.91 KMT2A (0.95) KMT2AMEN1MAPTALDH1A1CA12
Acetaminophen SCHEMBL5081499 0.91 KMT2A (0.95) KMT2AMEN1MAPTALDH1A1CA12
Acetaminophen SCHEMBL8207526 0.91 KMT2A (0.95) KMT2AMEN1MAPTALDH1A1CA12
Acetaminophen SCHEMBL31738441 0.91 KMT2A (0.95) KMT2AMEN1MAPTALDH1A1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114478609-A Method for applying thiophenol photocatalyst to defluorination alkylation or defluorination protonation reaction 中国科学技术大学 2022-05-13 CN claimed
CN-108103146-B Biosensor for detecting salmonella 济南大学 2021-08-17 CN claimed
CN-108169203-B Biosensor for detecting activity of hOGG1 and application thereof 济南大学 2020-09-08 CN claimed
CN-114478609-A Method for applying thiophenol photocatalyst to defluorination alkylation or defluorination protonation reaction 中国科学技术大学 2022-05-13 CN disclosed
CN-108103146-B Biosensor for detecting salmonella 济南大学 2021-08-17 CN disclosed
CN-108169203-B Biosensor for detecting activity of hOGG1 and application thereof 济南大学 2020-09-08 CN disclosed
CN-111217891-A Synthesis method of terlipressin 深圳翰宇药业股份有限公司 2020-06-02 CN disclosed
CN-110423302-A A kind of magnetic surface molecularly imprinted polymer and the preparation method and application thereof UNIV SOUTH CHINA 2019-11-08 CN disclosed
CN-109864965-A A kind of gold skin base solution composition 叶绿芝生物科技(中山)有限公司 2019-06-11 CN disclosed
CN-104897754-A Preparation method for carbon nano tube and 4.0-generation PAMAM covalence layer-by-layer self-assembly modified glassy carbon electrode UNIV NORTHWEST NORMAL 2015-09-09 CN disclosed
CN-101200659-B Additive composition INFINEUM INT LTD 2013-08-28 CN disclosed
CN-102060790-B Quinoxaline double N-oxide derivative ligand and application thereof in promotion on copper-catalyzed C-O coupling reaction SHANGHAI INST TECHNOLOGY 2013-01-09 CN disclosed
US-20120101164-A1 ABSCISSION AND CROP STORAGE UNIT TAMINCO, NAAMLOZE VENNOOTSCHAP (BE) 2012-04-26 US disclosed
CN-102060790-A Quinoxaline double N-oxide derivative ligand and application thereof to promotion on copper-catalyzed C-O coupling reaction SHANGHAI INST TECHNOLOGY 2011-05-18 CN disclosed
CN-101200659-A Additive composition INFINEUM INT LTD (GB) 2008-06-18 CN disclosed
CN-1240352-A Salts of acetaminophen MCNELL PPC INC (US) 2000-01-05 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120101164-A1 ABSCISSION AND CROP STORAGE UNIT BROX, ACR, ABAT KMT2A 4125/4885MEN1 4059/4885MAPT 953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.