Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2606369 | 0.83 | GNAI3 (0.42) | L3MBTL1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2606486 | 0.82 | HSD11B1 (0.54) | ALDH1A1MAPTMEN1KMT2AHSD11B1 | |
| SCHEMBL2666140 | 0.81 | GNAI3 (0.50) | L3MBTL1ALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL9072449 | 0.80 | EPHX2 (0.51) | ALDH1A1MAPTMEN1KMT2AHSD11B1 | |
| SCHEMBL2606383 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL2606418 | 0.78 | TPSAB1 (0.45) | ALDH1A1SMN1; SMN2NAMPT | |
| SCHEMBL2606484 | 0.76 | NPC1 (0.40) | L3MBTL1ALDH1A1MEN1KMT2AHSD11B1 | |
| SCHEMBL10272978 | 0.76 | MEN1 (0.43) | L3MBTL1ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL785756 | 0.76 | ALDH1A1 (0.41) | L3MBTL1ALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL2606485 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MAPTMEN1KMT2AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2444397-A1 | Heteroaryl-ureas and their use as glucokinase activators | Novo Nordisk A/S (DK) | 2012-04-25 | — | — | EP | disclosed |